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Article Abstract
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9644601 | PMC |
| http://dx.doi.org/10.1186/s13054-022-04213-8 | DOI Listing |
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Hyperoxia and End-Organ Complications Among Cardiogenic Shock Patients Supported by Veno-Arterial Extracorporeal Membrane Oxygenation.
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Division of Critical Care Cardiology, Department of Cardiovascular Medicine, Mayo Clinic Rochester Minnesota, Rochester, MN.
Objectives: To investigate whether severe hyperoxia predisposes to end-organ complications and whether these complications contribute to in-hospital mortality among cardiogenic shock (CS) patients supported in veno-arterial extracorporeal membrane oxygenation (VA-ECMO).
Design: Adult patients with CS from the Extracorporeal Life Support Organization Registry between 2010 and 2023 were categorized into normoxia (Pa o2 60-150 mm Hg), mild hyperoxia (Pa o2 151-300 mm Hg), and severe hyperoxia (Pa o2 > 300 mm Hg) based on their Pa o2 at 24 hours. The primary outcome was in-hospital mortality.
Association Between Arterial Hyperoxia and Mortality in Pediatric and Adult Patients Undergoing Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis.
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From the Department of Intensive Care Unit, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
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- The systematic review and meta-analysis aimed to evaluate the link between arterial oxygen levels (Pao2) and 28-day mortality among patients on ECMO support.
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Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation.
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Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, 553 St Kilda Road, Melbourne, VIC, 3004, Australia.
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New Insights into Hepatic and Intestinal Microcirculation and Pulmonary Inflammation in a Model of Septic Shock and Veno-Arterial Extracorporeal Membrane Oxygenation in the Rat.
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Department of Anesthesiology, Critical Care Medicine and Pain Therapy, University Hospital of Giessen, Justus-Liebig-University, 35392 Giessen, Germany.
Despite significant efforts toward improving therapy for septic shock, mortality remains high. Applying veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) in this context remains controversial. Since the cannulation of the femoral artery for V-A ECMO return leads to lower body hyperoxia, this study investigated the impact of V-A ECMO therapy on the intestinal and hepatic microcirculation during septic shock in a rodent model.
View Article and Find Full Text PDFOxygenation management during veno-arterial ECMO support for cardiogenic shock: a multicentric retrospective cohort study.
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Service de réanimation médicale, CHU Besançon, Besançon, France.
Backgound: Hyperoxemia is common and associated with poor outcome during veno-arterial extracorporeal membrane oxygenation (VA ECMO) support for cardiogenic shock. However, little is known about practical daily management of oxygenation. Then, we aim to describe sweep gas oxygen fraction (FO), postoxygenator oxygen partial pressure (PO), inspired oxygen fraction (FO), and right radial arterial oxygen partial pressure (PO) between day 1 and day 7 of peripheral VA ECMO support.
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