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Background: The Contrast Avoidance Model (Newman & Llera, 2011) proposes that worry is reinforced by avoiding a negative contrast and increasing the likelihood of a positive contrast.
Objective: To determine if reinforcement of worry occurs naturalistically via contrasts in both negative and positive emotion.
Method: Using event-contingent momentary assessment we assessed social interactions, pre-interaction state worry and pre-post interaction positive and negative emotion. Participants with generalized anxiety disorder (GAD; N = 83) completed an online questionnaire after social interactions lasting at least 1 min for 8 days. Three-level multilevel models were conducted.
Results: Higher worry was concurrently associated with increased negative emotion and decreased positive emotion. Regardless of pre-interaction worry level, negative emotion decreased, and positive emotion increased from before to after interactions, suggesting that most interactions were benign or positive. At lower levels of pre-interaction worry, participants experienced increased negative emotion and decreased positive emotion from before to after interactions. At higher levels of pre-interaction worry, participants experienced decreased negative emotion and increased positive emotion from before to after interactions.
Conclusion: Among persons with GAD, worrying before social interactions may be both negatively and positively reinforced; furthermore, not worrying before social interactions may be both negatively and positively punished.
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http://dx.doi.org/10.1016/j.janxdis.2022.102634 | DOI Listing |
JMIR Res Protoc
September 2025
Department of Development & Environmental Studies, Palacký University Olomouc, Olomouc, Czech Republic.
Background: Children in low- and middle-income countries face obstacles to optimal language and cognitive development due to a variety of factors related to adverse socioeconomic conditions. One of these factors is compromised caregiver-child interactions and associated pressures on parenting. Early development interventions, such as dialogic book-sharing (DBS), address this variable, with evidence from both high-income countries and urban areas of low- and middle-income countries showing that such interventions enhance caregiver-child interaction and the associated benefits for child cognitive and socioemotional development.
View Article and Find Full Text PDFPerspect Behav Sci
September 2025
ABA Clinic, United Kingdom of Great Britain and Northern Ireland, 40A Burgess Road, Southampton, SO16 7AH UK.
In recent years, the question has been raised as to whether teaching eye contact to autistic children is an ethically defensible educational objective. In the present article, I suggest that this question may be best answered by first defining contact with the eyes not as behavior, but as a consequence for the behavior of looking. Looking at people's faces, and in particular the eyes, provides information regarding the discriminative functions and reinforcing value of social stimuli, of people, of what they do, what they say, and what they feel, and is a critical part of all social behavior.
View Article and Find Full Text PDFFront Microbiol
August 2025
State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Autism spectrum disorders (ASD), a group of neurodevelopmental disorders characterized by the core symptoms of impaired social communication and stereotyped behaviors, is strongly associated with dysregulated microbiota-gut-brain axis. Emerging evidence suggests that , which showed reduced abundance in ASD cohorts, holds therapeutic potential, though its interaction with host remain unexplored. Here, we investigated the efficacy and molecular basis of 4P-15 (4P-15) in BTBR /J (BTBR) mice, an idiopathic ASD mouse model.
View Article and Find Full Text PDFBiol Psychiatry Glob Open Sci
November 2025
University of Basel, Department of Clinical Research (DKF), University Psychiatric Clinics, Translational Neurosciences, Basel, Switzerland.
Background: The hippocampus plays a critical role in psychosis, with reduced volume observed across the psychosis continuum. These structural changes are associated with cognitive deficits, symptom severity, and increased risk of psychosis progression. Elevated hippocampal perfusion and glutamate/GABA (gamma-aminobutyric acid) imbalance further suggest metabolic dysregulation as a key mechanism.
View Article and Find Full Text PDFClin Interv Aging
September 2025
Party Committee Office, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People's Republic of China.
Objective: Living alone is becoming increasingly common among the elderly population, and there is a close relationship between living alone and chronic diseases in relation to depression. However, the interplay between them has not been fully investigated. This study aims to explore the role of the number of chronic diseases in the relationship between living alone and depressive symptoms among older adults in China.
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