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Background: Colorectal (CRC) survivors often experience physical and psychological symptoms affecting their health-related quality of life (HRQoL). This study aimed to identify factors impacting HRQoL-related functioning and physical symptoms among adult Omani CRC survivors.
Methods: A cross-sectional study of 124 adult CRC survivors was conducted at the two main oncology referral hospitals in Oman. A validated Arabic version of the European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire 30 was used to collect data.
Results: A total of 118 CRC survivors participated in the study (response rate: 95.2%). The mean age was 52 years and there were an equal number of male and female participants (n = 59 each; 50.0%). A total of 62 survivors (52.5%) had been diagnosed with CRC at stages III or IV. The overall score for global health was high (81.7). With regards to functioning, high mean scores were observed for domains of role (91.0) and social (90.7) functioning. In terms of symptoms, high mean scores were reported for constipation (25.4), insomnia (25.1), pain (20.1), and fatigue (18.9). Survivors under 60 years old (β=15.5, p=.004) and those with no comorbidities (β=16.0, p=.001) demonstrated better functional HRQoL. Being male was predictive of better functional HRQoL in the emotional (β=13.9, p<0.008), cognitive functioning (β=12.5, p=.013), role functioning (β=14.0, p=0.006) and physical functioning (β=17.8, p<0.001) domains.
Conclusions: Healthcare professionals in Oman should implement measures to enhance the HRQoL of CRC survivors, particularly women and those with coexisting morbidities.
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http://dx.doi.org/10.31557/APJCP.2022.23.9.3019 | DOI Listing |
Med Sci (Basel)
August 2025
Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, 1082 Budapest, Hungary.
Background/objectives: Although numerous prognostic biomarkers have been proposed for colorectal cancer (CRC), their longitudinal evaluation remains limited. The aim of this study was to investigate longitudinal changes in biomarkers calculated from routinely used laboratory markers and their relationships to common chronic diseases (comorbidities).
Methods: A retrospective longitudinal observational study was completed with the inclusion of 817 CRC patients and a total of 4542 measurement points.
Purpose: Patients with colorectal cancer (CRC) undergoing chemotherapy often face symptoms that significantly diminish their quality of life. Dietary intake is one factor that affects both physical and psychological CRC symptom management; however, notable inequities in CRC symptom experiences exist due to social determinants of health (SDOH). This study aimed to explore the challenges and adaptative behaviors related to dietary management and treatment-related symptom experiences among patients with CRC undergoing chemotherapy, with a particular focus on the influence of SDOH.
View Article and Find Full Text PDFJ Cancer Surviv
August 2025
Department of Neurology, The First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou City, Jiangsu, 215006, P.R. China.
Objective: This study evaluates the effects of combined psychological intervention and enhanced nutritional support on postoperative recovery in CRC patients, focusing on nutritional status, sleep quality, pain management, psychological well-being, and quality of life.
Methods: A randomized controlled trial was conducted at the First Affiliated Hospital of Soochow University from August 2021 to August 2023. A total of 300 CRC patients who underwent surgery were randomly assigned to the observation group (150 patients), receiving standard postoperative care plus psychological intervention and enhanced nutritional support, or the control group (150 patients), receiving standard care only.
J Natl Cancer Inst
August 2025
Ann & Robert H. Lurie Children's Hospital, Chicago, IL, USA.
Mortality after diagnosis of colorectal subsequent malignant neoplasms (CRC-SMN) among childhood cancer survivors is understudied. Using data from the Childhood Cancer Survivor Study (CCSS) and the Surveillance, Epidemiology, and End Results (SEER) program, we compared all-cause mortality of survivors with CRC-SMN to survivors without CRC-SMN and CRC patients in the general population without a childhood cancer history. Among 25,656 childhood cancer survivors, 96 developed CRC-SMN, with 50% diagnosed before age 40 and 19% before age 30.
View Article and Find Full Text PDFWorld J Gastrointest Oncol
August 2025
Department of Medical Oncology, Habib Bourguiba University Hospital, University of Sfax, Sfax 3008, Tunisia.
Background: As the population of colorectal cancer (CRC) survivors continues to grow, the demand for effective, evidence-based post-treatment strategies becomes increasingly urgent. Despite robust evidence linking lifestyle factors to cancer outcomes, there remains no established consensus on the optimal nutritional and physical activity (PA) guidelines for disease-free CRC survivors.
Aim: To demonstrate that structured lifestyle interventions, specifically tailored dietary and PA programs, can significantly improve behavioral targets as well as disease-free and overall survival (OS).