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The rise in cases of antibiotic resistance can be mainly attributed to the overuse and misuse of antibiotics. To address this issue, the WHO launched Access, Watch, and Reserve (AWaRe) classification of antibiotics in 2017 as a surveillance tool. Many countries have adopted it to monitor and optimize their antibiotic usage. However, implementation of it is yet not seen at a very appreciable level. Through this survey, we tried to explore the prescribing pattern of antibiotics based on the WHO AWaRe classification in selected secondary and tertiary care health facilities of Tamil Nadu. In-patient case sheets were audited in selected departments across 18 health facilities in six districts. Proportionately higher use of the watch group of antibiotics was found in all the districts. A lower access-watch ratio suggests the need for judicious implementation of such tools to safeguard this life-saving good and ensuring its sustainability.
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http://dx.doi.org/10.4103/ijph.ijph_274_22 | DOI Listing |
JAMA Netw Open
September 2025
Centre de recherche intégrée pour un système apprenant en santé et services sociaux, Centre intégré de santé et de services sociaux de Chaudière-Appalaches, Lévis, Québec, Canada.
Importance: Caregivers of community-dwelling older adults play a protective role in emergency department (ED) care transitions. When the demands of caregiving result in caregiver burden, ED returns can ensue.
Objective: To develop models describing whether caregiver burden is associated with ED revisits and hospital admissions up to 30 days after discharge from an initial ED visit.
J Urban Health
September 2025
Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Timely access to comprehensive , high-quality emergency obstetric and neonatal care can prevent maternal and neonatal mortality but remains challenging in Benin. We examine geographic accessibility to childbirth care (CBC) in Grand Nokoué, the largest conurbation in Benin. We gathered data on boundaries, health facilities, road network, elevation, land cover, relative wealth, urbanicity, and geo-traced travel speeds over 45 days during the rainy season.
View Article and Find Full Text PDFMetabolomics
September 2025
Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.
Introduction: Knockout of the Fmo5 gene in mice led to a lean, slow-ageing phenotype characterised by the presence of 2,3-butanediol isomers in their urine and plasma. Oral treatment of wildtype mice with 2,3-butanediol led to a low cholesterol, low epididymal fat phenotype.
Objectives: Determine if significant, heterozygous coding variations in human FMO5 would give rise to similar clinical and metabolic phenotypes in humans, as in C57BL/6J mice with knockout of the Fmo5 gene and in particular, increased excretion of 2,3-butanediol.
J Robot Surg
September 2025
Department of Research and Innovation, Medway NHS Foundation Trust, Gillingham, ME7 5NY, UK.
Robotic surgery has transformed the field of surgery, offering enhanced precision, minimal invasiveness, and improved patient outcomes. This narrative review explores the multifaceted aspects of robotic surgery, examining the challenges, recent advances, and future prospects for its integration into healthcare. Our comprehensive analysis of 48 studies reveals significant geographic disparities in robotic surgery research and implementation, with 68.
View Article and Find Full Text PDFParasitol Res
September 2025
Laboratório de Parasitologia, Instituto Biomédico, Universidade Federal Fluminense (UFF), Bloco E, 5º Andar, 510-525,Outeiro São João Batista S/N, Niterói, Rio de Janeiro, 24020-141, Brazil.
Brazil is a major pig-producing country with production systems that include both industrial and family farms. In these facilities, parasitic diseases present an obstacle to production. This study aimed to estimate the prevalence and risk factors of the gastrointestinal parasites that infect pigs as well as to provide information for producers through extension activities.
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