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and are species native to the Amazonian, traded by extractivists to obtain coumarin. We aimed to analyze the presence of coumarin in the ethanolic extracts of leaves, branches and fruits of and and to evaluate the antimicrobial activity of these extracts against phytopathogenic fungi and bacteria of clinical interest. Chemical analyses were performed by thin layer chromatography (TLC) and by gas chromatography coupled to mass spectrometry (GC-MS). For the antifungal assays, the fungi used were , , two isolates of spp. and , and the antibacterial assay was performed using the minimum inhibitory concentration (MIC) test with , , and bacteria. In seed extracts and in husks, endocarps, and seeds, we identified 1,2-benzopyrone. endocarp extracts and seeds provided the greatest decrease in mycelial growth of the evaluated phytopathogens, showing promise as an alternative control. The husk and endocarp extracts of both species had a weak effect on . This research is the first to compare the different parts of species of the genus and to evaluate the use of husks and endocarps of fruits to obtain coumarin. Chemical analyses used to quantify the compounds existing in the extracts, and tests with phytopathogens in vitro and in vivo are currently being carried out.
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http://dx.doi.org/10.3390/molecules27185837 | DOI Listing |
Drug Dev Res
September 2025
Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu Provincial Research Center for Medicinal Function Development of New Food Resources, Jiangsu University, Zhenjiang, Jiangsu, China.
Liver cancer is the fourth most deadly cancer worldwide, but existing treatment options are insufficient, thus highlighting the urgent need for new therapeutic agents. Taxanes, known for their anticancer properties, provide a promising avenue for intervention. In this study, a tetracyclic taxane compound with antitumor activity (taxinine) was extracted and isolated from Taxus chinensis (T.
View Article and Find Full Text PDFBlack raspberry is known to contain a diverse number of phytochemicals, especially polyphenols which have shown health benefits. These compounds might play a role in alleviating β-amyloid (Aβ)-induced neurotoxicity. In this study, we investigated the effect of black raspberry in reducing Aβ toxicity and improving mitochondrial function in the HT-22 cell model.
View Article and Find Full Text PDFJ Parasitol Res
August 2025
Department of Biology, Wachemo University, Hossana, Ethiopia.
Environmental changes due to global warming and human activities have negatively impacted malaria vector control in Hadiya zone, Ethiopia. Plants contain anthraquinoes. Flavonoids, glycosides, phenol, saponin, steroids, tannin, and terpenes that are target specific, rapidly biodegradable, ecofriendly, and less toxic to human health.
View Article and Find Full Text PDFAnal Chim Acta
November 2025
Multidisciplinary Laboratory of Food and Health (LabMAS), School of Applied Sciences (FCA), Universidade Estadual de Campinas (UNICAMP), Rua Pedro Zaccaria 1300, Limeira, 13484-350, São Paulo, Brazil. Electronic address:
Background: Monitoring industrial processes is critical for ensuring consistent product quality, as consumers expect uniformity across different production batches. In the case of herbal extracts, such as rosemary hydroalcoholic extracts, it is essential to control the yield of target compounds to maintain both the expected quality and safety. Typically, these extracts are produced in an extractor and then analyzed separately in a laboratory (offline).
View Article and Find Full Text PDFPhytochemistry
September 2025
State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Guizhou Medical University, Natural Products Research Center of Guizhou Province, Guiyang 550014, China. Electronic address:
Seven previously undescribed glycosides, including four iridoid glycosides (1, 2, 4, and 5), three phenolic glucosides (18, 21, and 22), together with nineteen known compounds, were isolated from the ethanol extract of Gentiana rhodantha Franch. Their structures were determined by analysis of 1D and 2D NMR, HRESIMS, X-ray diffraction, NMR calculation, and electronic circular dichroism (ECD) calculation. Among them, compound 21 was a novel highly rearranged endo-phenolic analogue with a unique skeleton.
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