98%
921
2 minutes
20
Objectives: To assess whether the King-Devick (KD) test is useful as a prognostic test for prolonged concussion symptoms by examining the relationship between a) change in performance on KD test from baseline to within two days post-injury and b) the absolute KD time at post-concussion testing, with an outcome of time to return to play (RTP).
Design: Prospective Cohort Study.
Methods: Collegiate varsity athletes in the Concussion Assessment, Research, and Education (CARE) Consortium completed baseline and post-injury King-Devick tests from 2014 to 2018. Two exposures were evaluated: 1) change in KD score from baseline to within two days post-injury and 2) absolute KD score within two days post-injury, adjusted for baseline KD. We used Cox proportional hazards models to analyze the relationships between these exposures and time to RTP post-concussion.
Results: A total of 309 concussion injuries were included. Median baseline KD score was 40.0 s (IQR: 35.8, 45.2). Median post-injury KD score was 45.8 s (IQR: 39.8, 57.1). Median number of days until RTP in this cohort was 11 (IQR: 8, 17). Post-injury KD score adjusted for baseline KD had a stronger association with time to RTP duration (HR: 0.99 (0.98, 1.00), p = 0.03) than the difference in KD score from baseline to post-injury (HR: 0.99 (0.99, 1.00), p = 0.07).
Conclusions: Higher post-injury KD scores are associated with longer RTP. The association between KD post-concussion test and longer RTP warrants further investigation to assess the utility of the KD for prognostication in a clinical setting.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.jsams.2022.08.012 | DOI Listing |
Perfusion
September 2025
Department of Adult Critical Care, Guy's and St Thomas' NHS Foundation Trust, London, UK.
IntroductionWe report the successful use of erector spinae (ESP) plane block in the management of a patient with severe respiratory failure secondary to chest trauma requiring invasive ventilation and Veno-venous extracorporeal membrane oxygenation (V-V ECMO).Case reportA 64-year-old man with flail chest and severe respiratory failure required V-V ECMO. An ESP plane block on day 3 enabled extubation, mobilisation, and secretion clearance, leading to ECMO weaning after six days and discharge 18 days post-injury.
View Article and Find Full Text PDFJ Neurol Sci
September 2025
Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, United States of America.
Background: A key limitation of the IMPACT model for prognostication after severe traumatic brain injury (TBI) is the use of predictors from hospital admission only. We sought to identify if including daily blood labs (e.g.
View Article and Find Full Text PDFBiomater Adv
September 2025
Department of Anesthesiology, Ganzhou Key Laboratory of Anesthesiology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China. Electronic address:
Spinal cord injury (SCI) is exacerbated by the formation of an acidic microenvironment and extensive neuronal loss, both of which contribute to poor functional recovery. To address this, we developed lysine-polydopamine nanoparticles (Lys-PDA) as a multifunctional therapeutic platform for SCI. Lysine, a naturally occurring amino acid, possesses weak alkalinity and neuroprotective properties, but suffers from poor in vivo stability and non-specific distribution.
View Article and Find Full Text PDFTraumatic brain injury (TBI) elicits a sustained innate immune response involving both resident microglia and infiltrating peripheral immune cells. However, the influence of peripheral immune-derived signals on microglial dynamics and functional recovery remains poorly understood. We previously identified the receptor tyrosine kinase EphA4 as a regulator of acute neuroinflammation following TBI.
View Article and Find Full Text PDFJ Shoulder Elbow Surg
September 2025
University of Calgary, Calgary, Alberta, Canada; South Health Campus Research Unit for Bone and Soft Tissue, Calgary, Alberta, Canada.
Background: Surgical treatment options for distal biceps tendon ruptures vary based on time from injury to surgery. While direct repair (DR) is preferred for acute injuries, high flexion angle repair (HFA) and allograft reconstruction (AR) are alternatives for chronic cases. This study examines the relationship between time to surgery, surgical technique selection, and complication rates.
View Article and Find Full Text PDF