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Introduction And Hypothesis: As a consequence of the evolution of surgery in reconstructive techniques, cervicovaginal reconstruction has become an option for patients diagnosed with congenital cervical and vaginal atresia. This study was aimed at comparing long-term clinical and anatomical results in patients who had cervicovaginal reconstruction with either a small intestinal submucosa (SIS) graft or a split-thickness skin (STS) graft.
Methods: This was a retrospective study of 34 patients who underwent cervicovaginal reconstruction using SIS or STS grafts between January 2012 and August 2017. The patients' postoperative resumption of menstruation, vaginal length, body image satisfaction, and sexual satisfaction were assessed. Quantitative and categorical variables were compared using Student's t test and Chi-squared test respectively.
Results: The mean follow-up time was 81.29 ± 20.69 months. The SIS group had a shorter surgery time, an earlier return to work, and a higher cost (p < 0.05). All patients resumed menstruation, but 4 patients were diagnosed with cervical stricture. There was no significant difference in the length of the neovagina, and the satisfaction score of the sexual life of patients and their sexual partners was similar in both groups. Patients in the SIS group showed greater satisfaction with their bodies (p < 0.001). One patient in the SIS group got pregnant via assisted-reproduction techniques.
Conclusions: Cervicovaginal reconstruction using SIS or STS grafts is an effective treatment for patients diagnosed with congenital cervical and vaginal atresia. The method of SIS graft is simpler, with less surgical injury and greater body satisfaction, but it is more expensive.
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http://dx.doi.org/10.1007/s00192-022-05327-x | DOI Listing |
Zhonghua Yi Xue Za Zhi
August 2025
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai 200433, China.
To compare the long-term outcomes of cervicovaginal reconstruction between using small intestinal submucosa (SIS) grafts and using autologous lateral femoral split-thickness skin substitutes (STS) grafts. This was a prospective cohort study, involving 81 patients with obstructive cervical dysplasia who underwent cervicovaginal reconstruction using either SIS or STS grafts from January 2012 to August 2024. Data were collected, including demographic characteristics, operative duration, hospitalization costs, postoperative menstrual recovery, pregnancy outcomes, reoperation rates, vaginal length, and other relevant clinical parameters.
View Article and Find Full Text PDFFront Med (Lausanne)
July 2025
Lebanese American University Medical Center -Rizk Hospital, Beirut, Lebanon.
Cervicovaginal anomalies are rare and form 4-7% of the Müllerian anomalies. Traditionally, cervicovaginal agenesis/dysgenesis had been treated by hysterectomy due to the high risks of restenosis and sepsis which are associated with cervical canalization. In this work, we report the case of a 14-year-old patient who presented with amenorrhea and cyclic abdominal pain.
View Article and Find Full Text PDFGynecol Minim Invasive Ther
May 2025
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Congenital cervical and vaginal atresia in the presence of a functioning endometrium is an extremely rare disease. Cervicovaginal reconstruction preserves fertility for these patients. We present the case of a 20-year-old patient who had cervicovaginal reconstruction 7 years ago due to congenital cervical and vaginal aplasia.
View Article and Find Full Text PDFGels
March 2025
Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, 825 Fairfax Avenue, Suite 526, Norfolk, VA 23507-2007, USA.
Vulvovaginal symptoms affect up to 39% of women. These symptoms have a significant impact on quality of life and are often linked to imbalances in the vaginal microbiota. This study evaluates the therapeutic efficacy of a zinc-containing hydroxyethyl cellulose-based hydrogel in 37 women with different vulvovaginal symptoms (itching, burning, irritation, pain, dryness, discharge, and odor).
View Article and Find Full Text PDFJ Plast Reconstr Aesthet Surg
October 2023
Department of Plastic Surgery, Far Eastern Memorial Hospital, Taipei, Taiwan. Electronic address: