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Cord compression and ischemic non-compressive myelopathy are a complication of spinal Paget's disease (SPD). SPD usually touches a single spine level. We report an unusual case with bilevel spinal cord compression and dysfunction which was medically treated due to resolution of the vascular steal syndrome.
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http://dx.doi.org/10.1002/ccr3.6263 | DOI Listing |
Urol Case Rep
September 2025
Austin Health, Heidelberg, VIC, Australia.
We report a 43-year-old man with de novo metastatic testicular seminoma complicated by paraplegia from spinal cord compression due to retroperitoneal lymphadenopathy. Urgent retroperitoneal biopsy confirmed seminoma and, after the patient declined neurosurgical intervention, systemic chemotherapy was promptly initiated prior to delayed orchidectomy. Post-chemotherapy orchidectomy histology revealed minimal viable tumour and serial imaging showed a residual retroperitoneal mass with low-grade uptake on FDG-PET.
View Article and Find Full Text PDFFront Nucl Med
August 2025
School of Health Sciences and Social Work, Griffith University, Brisbane/Gold Coast, QLD, Australia.
Background: Animal models of nerve compression have revealed neuroinflammation not only at the entrapment site, but also remotely at the spinal cord. However, there is limited information on the presence of neuroinflammation in human compression neuropathies. The objectives of this study were to: (1) assess which tracer kinetic model most optimally quantified [C]DPA713 uptake in the spinal cord and neuroforamina in patients with painful cervical radiculopathy, (2) evaluate the performance of linearized methods (e.
View Article and Find Full Text PDFInt J Radiat Oncol Biol Phys
October 2025
Department of Central Nervous System Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Int J Radiat Oncol Biol Phys
October 2025
Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin.
World Neurosurg
September 2025
Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing 400037, China. Electronic address:
Objective: The purpose of this study is to present five new cases of congenital absence of posterior elements of the axis (C2), totaling 17 cases report in the literature, and to propose an anatomical classification system for this rare condition for standardizing its management.
Methods: A retrospective review of five patients diagnosed and surgically treated for the absence of C2 posterior elements was conducted from 2017 to 2024. Clinical characteristics were summarized, and imaging studies, including X-rays, CT, and MRI were performed to define abnormalities and cord compression.