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Purpose: To test the applicability of autofluorescence (AF) spectrum and image in the detection and identification of oral pathogens.
Methods: Oral pathogens (Candida albicans, Porphyromonas gingivalis, Streptococcus mutans) and teeth were used. To induce AF, the 405 nm laser was used as a light source, and AF was obtained and observed using a spectrometer, fluorescence camera, and microscope, respectively.
Results: The tested oral pathogens had similar spectral distributions, but their peak intensities and peak ratios were different. Their peak positions and spectral patterns were different from those of the tested sound and carious teeth. These differences were also found from the other referenced oral mucosa. Fluorescence image could localize the existence of oral bacteria. Oral pathogens could be imaged by fluorescence, but identification of each pathogen by image was not probable.
Clinical Significance: Oral pathogens can be observed and identified from the lesion if autofluorescence spectrum and fluorescence images are combined.
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mBio
September 2025
Department of Microbiology, Haukeland University Hospital, Bergen, Norway.
Unlabelled: There is a considerable interest in the association between and colorectal cancer (CRC). Recently, it was suggested that this association is valid only for a distinct clade of ( C2) and that strains belonging to another clade ( C1) are only associated with the oral cavity. It was further suggested that this made C1 a natural comparator when looking for candidate genes associated with the pathogenicity of C2.
View Article and Find Full Text PDFJ Oral Microbiol
September 2025
Department of Pediatric Dentistry, Yonsei University College of Dentistry, Seoul, Republic of Korea.
Background: The neonatal period is critical for oral microbiome establishment, but temporal patterns in preterm newborns remain unclear. This study examined longitudinal microbiome changes in full-term and preterm newborns and assessed perinatal and clinical influences.
Methods: Oral swabs were collected from 98 newborns (23 full-term, 75 preterm).
Front Microbiol
August 2025
Department of Immunology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
The genus is a heterogenous group of commensal and pathogenic bacteria. Members of this genus are classified into two major groups, the pyogenic group and the viridans group streptococci (VGS). VGS are frequently found as normal members of the human microbiome and are regarded as commensals.
View Article and Find Full Text PDFFront Oral Health
August 2025
Conservative Dentistry and Endodontics, AB Shetty Memorial Institute of Dental Sciences, Nitte (deemed to be) University, Mangalore, India.
Short-chain fatty acids (SCFAs), primarily acetate (C2), propionate (C3), and butyrate (C4), are crucial microbial metabolites formed by the fermentation of dietary fibers by gut microbiota in the colon. These SCFAs, characterized by fewer than six carbon atoms, serve as an essential energy source for colonic epithelial cells and contribute approximately 10% of the body's total energy requirement. They are central to maintaining gut health through multiple mechanisms, including reinforcing intestinal barrier function, exerting anti-inflammatory effects, regulating glucose and lipid metabolism, and influencing host immune responses.
View Article and Find Full Text PDFFront Vet Sci
August 2025
Faculty of Veterinary Medicine, Lusófona University-Lisbon University Centre, Lisbon, Portugal.
Introduction: is a well-recognized etiologic agent of upper respiratory tract disease in tortoises. Although frequently reported in both captive and wild populations across Europe, its occurrence in Portugal had not been previously documented. This study aimed to investigate the presence of in apparently healthy captive tortoises in mainland Portugal and to evaluate potential host- and management-related factors associated with infection.
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