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http://dx.doi.org/10.1038/s41371-022-00745-2 | DOI Listing |
Glob Heart
September 2025
Department of Health Service Research and Policy, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Cardiovascular diseases (CVDs) are the leading global cause of mortality, with treatment adherence posing a major barrier to effective prevention and control. Single pill combinations (SPCs), also known as fixed-dose combinations, simplify treatment by combining multiple agents into one pill, improving adherence and reducing cardiovascular risk. This World Heart Federation Roadmap synthesizes the latest clinical evidence and identifies key barriers to SPC implementation, including limited manufacturing, affordability, regulatory complexity, and inconsistent guideline inclusion.
View Article and Find Full Text PDFLancet Public Health
August 2025
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins University, Baltimore, MD, USA; Center for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, Baltimo
Background: In 2018, the Philippines implemented a tax on sugar-sweetened beverages. A broader tax on unhealthy foods is being considered. We aimed to estimate the effect of a tax on unhealthy packaged foods.
View Article and Find Full Text PDFLancet Glob Health
September 2025
Department of Internal Medicine, Division of Nephrology and Transplantation, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam 3015 GD, Netherlands. Electronic address:
EClinicalMedicine
August 2025
Division of Nephrology, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Background: Infections are a major cause of hospitalization in people with chronic kidney disease (CKD), with incidence similar to cardiovascular disease, yet the risk of infection has not been systematically studied across stages of CKD.
Methods: We conducted a meta-analysis of individual participant data including 1,246,912 individuals across 47 cohorts in the CKD Prognosis Consortium, with information on estimated glomerular filtration rate based on serum creatinine (eGFRcr) and urinary albuminuria (ACR) (or proteinuria converted to ACR), to examine the association of eGFR and ACR with the risk of hospitalization with infection. Outcomes were ascertained through diagnostic codes on hospital discharge records relevant to acute infections (i.
AbstractSolid organ transplants save lives, but demand for transplantable organs outpaces supply. Traditionally, organs from patients infected with the Hepatitis C virus (HCV) were ineligible for donation to recipients without HCV (HCV D+/R- transplants) owing to concerns about intentionally transmitting HCV to organ recipients. New direct-acting antivirals against HCV and increased HCV+ organs from the opioid epidemic promised to solve the organ shortage.
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