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The article deals with an overview of acute extremity compartment syndrome with a focus on the option of non-invasive detection of the syndrome. Acute extremity compartment syndrome (ECS) is an urgent complication that occurs most often in fractures or high-energy injuries. There is still no reliable method for detecting ECS. The only objective measurement method used in clinical practice is an invasive measurement of intramuscular pressure (IMP). The purpose of this paper is to summarize the current state of research into non-invasive measurement methods that could allow simple and reliable continuous monitoring of patients at risk of developing ECS. Clinical trials are currently underway to verify the suitability of the most studied method, near-infrared spectroscopy (NIRS), which is a method for measuring the local oxygenation of muscle compartments. Less explored methods include the use of ultrasound, ultrasound elastography, bioimpedance measurements, and quantitative tissue hardness measurements. Finding a suitable method for continuous non-invasive monitoring of the syndrome would greatly improve the quality of care for patients at risk. ECS must be diagnosed quickly and accurately to prevent irreversible tissue damage that can occur within hours of syndrome onset and may even warrant amputation if neglected.
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http://dx.doi.org/10.3389/fbioe.2022.801586 | DOI Listing |
Trauma Surg Acute Care Open
September 2025
CRT 4, US Army Institute of Surgical Research Burn Center, Fort Sam Houston, Texas, USA.
Acute extremity compartment syndrome (CS) is a serious medical complication triggered by factors such as trauma, vascular injury, or prolonged compression, resulting in elevated intracompartmental pressure (ICP) and tissue ischemia. Diagnosis remains challenging, mainly relying on the subjective evaluation of clinical symptoms. Different animal models have been used to study pathophysiology and evaluate diagnostic and therapeutic approaches.
View Article and Find Full Text PDFAnn Med Surg (Lond)
September 2025
Department of Orthopedics, National Trauma Center, Kathmandu, Nepal.
Introduction: Snakebites, recognized as a neglected tropical disease by the WHO, cause significant morbidity and mortality globally. Although antivenom is the primary treatment, managing complications like compartment syndrome (CS) and soft tissue necrosis remains challenging. This case report describes a 39-year-old woman who developed CS following a green pit viper bite and subsequent antivenom administration, necessitating a fasciotomy.
View Article and Find Full Text PDFJ Plast Surg Hand Surg
August 2025
Department of Plastic and Hand Surgery, University Hospital Zurich, Switzerland.
Introduction: Patients undergoing curative treatment for soft-tissue sarcomas (STS) of the thigh bear the risk of developing lymphatic fistula and lymphedema. Innovative microsurgical concepts such as primary preventive lymphatic reconstruction show promising results. To discuss the likelihood of lymphatic complications after limb-preserving treatment of STS in the era before lymphatic reconstructive surgery and depending on the sarcoma location in the thigh became paramount in treating these patients.
View Article and Find Full Text PDFJAAPA
September 2025
At the Brooke Army Medical Center in Fort Sam Houston, TX, Major Naikeya H. Coston is an orthopedic PA fellow, Colin M. Dunderdale practices orthopedics, and Lieutenant Colonel Jeanne C. Patzkowski is chair of the department of orthopedic surgery. The authors have disclosed no potential conflicts of
Popliteal artery entrapment syndrome (PAES) is a form of vascular compromise that is characterized by compression of the popliteal artery by the muscular structures of the popliteal fossa. The underlying etiology of this condition stems from both congenital and functional mechanisms. This case report describes a patient with an insidious onset of bilateral leg pain, who was initially diagnosed with chronic exertional compartment syndrome and later found to have PAES.
View Article and Find Full Text PDFMicrosurgery
September 2025
Department of Plastic and Reconstructive Surgery, MedStar Georgetown University Hospital, Washington, DC, USA.
Background: Patients with only peroneal artery blood supply to the foot, known as peronea arteria magna (PAM), represent a rare cohort and a unique challenge in the setting of complex lower free (LE) tissue transfer (FTT). The present study aims to leverage a high volume lower extremity reconstruction center to determine the incidence and microsurgical considerations in PAM.
Methods: A retrospective cohort study was conducted at a single tertiary limb salvage center, reviewing all patients who underwent lower LE FTT from July 2011 to January 2024.