Article Synopsis
- Research focused on the impact of a palaeolithic diet on sleep apnoea in overweight postmenopausal women.
- Seventy women participated in a 2-year study, with one group following a palaeolithic diet and the other a low-fat control diet.
- Results showed that the palaeolithic diet led to significantly more weight loss (7.2 kg vs. 3.9 kg), which was linked to a reduction in sleep apnoea severity, though daytime sleepiness remained unchanged.
- To achieve a noticeable improvement in sleep apnoea, participants needed to lose at least 8 kg, highlighting the importance of weight loss in managing this condition.
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Article Abstract
Background/objectives: Obesity is the main risk factor for obstructive sleep apnoea, commonly occurring in females who are overweight after menopause. We aimed to study the effect of a palaeolithic diet on sleep apnoea in females with overweight after menopause from the population.
Methods: Seventy healthy, non-smoking females with a mean age of 60 years and a mean BMI of 33 kg/m were randomised to a palaeolithic diet or to a control low-fat diet according to Nordic Nutritional Recommendations, for 2 years. The apnoea-hypopnoea index was measured and daytime sleepiness was estimated during the intervention.
Results: The mean apnoea-hypopnoea index at baseline was 11.6 (95% CI 8.6-14.5). The mean weight loss was 7.2 kg (95% CI 5.3-9.2 kg) in the palaeolithic diet group and 3.9 kg in the control group (95% CI 1.9-5.9 kg); p < 0.021 for the group difference. The reduction in weight corresponded to a reduction in the apnoea-hypopnoea index in the palaeolithic diet group (r = 0.38, p = 0.034) but not in the control group (r = 0.08, p = 0.69). The apnoea-hypopnoea index was reduced in the palaeolithic diet group when the weight was reduced by more than 8 kg. Daytime sleepiness according to the Epworth Sleepiness Scale score and the Karolinska Sleepiness Scale score was unaffected by dietary group allocation.
Conclusions: A substantial decrease in body weight of 8 kg was needed to achieve a reduction in sleep apnoea in this small trial of women who are overweight after menopause. The palaeolithic diet was more effective for weight reduction than a control low-fat diet and the reduction in sleep apnoea was related to the degree of weight decrement within this diet group.
Trial Registration: Clinicaltrials.gov: NCT00692536.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492533 | PMC |
| http://dx.doi.org/10.1038/s41366-022-01182-4 | DOI Listing |
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