98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704826 | PMC |
http://dx.doi.org/10.1164/rccm.202203-0507ED | DOI Listing |
Zhongguo Zhong Yao Za Zhi
July 2025
Institute of Executive Development,National Medical Products Administration Beijing 100073, China.
Since the promulgation of the first Drug Administration Law of the People's Republic of China 40 years ago in 1984, China has undergone four main stages in the traditional Chinese medicine(TCM) regulation: the initial establishment of TCM regulation rules(1984-1997), the formation of a modern TCM regulatory system(1998-2014), the reform of the review and approval system for new TCM drugs(2015-2018), and the construction of a scientific regulation system for TCM(2019-2024). Over the past five years, a series of milestone achievements of TCM regulation in China have been achieved in the six aspects, including its strategic objectives and the establishment of a science-based regulatory system, the reform of the review and approval system for new TCM drugs, the optimization and improvement of the TCM standard system and its formation mechanism, comprehensive enhancement of regulatory capabilities for TCM safety, international harmonization of TCM regulation and its role in promoting innovation. Looking ahead, centered on advancing TCMRS to establish a sound regulatory framework tailored to the unique characteristics of TCM, TCM regulation will evolve into new reform patterns, advancing and extending across eight critical fronts, including the legal framework and policy architecture, the review and approval system for new TCM drugs, the quality standard and management system of TCM, the comprehensive quality & safety regulation and traceability system, the research and transformation system for TCMRS, AI-driven innovations in TCM regulation, the coordination between high-quality industrial development and high-level regulation, and the leadership in international cooperation and regulatory harmonization.
View Article and Find Full Text PDFFoods
August 2025
Center for Ecological-Noosphere Studies, NAS RA, Yerevan 0025, Armenia.
Chlorpyrifos (CPF) is a widely used organophosphate insecticide; however, global concerns exist regarding its potential health risks, particularly developmental neurotoxicity. This study aimed to determine CPF residues in locally sourced tomatoes and cucumbers and assess the potential chronic and acute dietary risks associated with their consumption by the adult population of Armenia. As part of the national residue monitoring program, samples of the two most commonly consumed vegetables (tomato and cucumber) were collected from various regions of Armenia and analyzed using gas chromatography-tandem mass spectrometry (GC-MS/MS).
View Article and Find Full Text PDFFront Public Health
August 2025
Department of Behavioral and Community Health Sciences, School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States.
Introduction: Alcohol-involved sexual violence on college campuses is a complex public health challenge shaped by interacting individual, interpersonal, social, and institutional factors. This paper presents a systems science-based theory of change for addressing alcohol-involved sexual violence, developed through collaborative modeling with campus collaborators as part of the CAMPUS (Collaborative Model-building Project to Understand Sexual Violence) study.
Methods: This study presents a stock-and-flow diagram (SFD) theory of change developed by a research team through the synthesis of three causal loop diagrams co-produced by three cohorts of students and practitioners across five college campuses.
J Xenobiot
August 2025
National Research and Development Institute for Industrial Ecology-ECOIND, Drumul Podu Dambovitei Street 57-73, 060652 Bucharest, Romania.
Per- and polyfluoroalkyl substances (PFAS) are a global concern due to their persistence, ubiquity, and accumulation in living organisms. Found in soils, biosolids, water, and the food chain, they pose health risks such as hormone disruption, immune damage, reproductive issues, and cancer. Regulations mainly target older PFAS like PFOA and PFOS, while many newer PFAS, including breakdown products, are poorly understood in terms of distribution, behavior, and toxicity.
View Article and Find Full Text PDFJ Environ Manage
August 2025
Section of Design for Sustainability, Department of Civil and Mechanical Engineering, Technical University of Denmark, Kongens Lyngby, Denmark; Centre for Absolute Sustainability, Technical University of Denmark, Kongens Lyngby, Denmark. Electronic address:
In response to growing environmental pressures, companies are increasingly required to develop comprehensive climate transition plans aligned with their science-based targets. However, a harmonized definition for these transition plans is lacking across existing frameworks, and effective corporate disclosure is still limited. This study examines 14 prominent frameworks for corporate climate transition, identifying key components that define transition plans and analysing how disclosure requirements shape expectations for corporate decarbonization.
View Article and Find Full Text PDF