Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Juvenile psammomatoid ossifying fibroma (JPOF) is an uncommon benign fibro-osseous lesion that only rarely presents in the calvaria.
Observations: The authors reported a case of JPOF in the left parietal bone of a 20-year-old patient and reviewed the 27 other cases of JPOF occurring in the calvaria as reported in the literature.
Lessons: JPOF rarely presents in the calvaria, and because diagnosis is a histopathologic one, clinicians should consider this entity when presented with a lytic, expansile mass on imaging. Little is known about the molecular mechanisms driving development of JPOF. amplification may play a role, although this was not seen in the case presented herein.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265227 | PMC |
| http://dx.doi.org/10.3171/CASE21361 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Juvenile ossifying fibroma in a 24-year-old female with systemic comorbidities: a rare case report.
Ann Med Surg (Lond)
September 2025
Faculty of Medicine, Damascus University, Damascus, Syrian Arab Republic.
Introduction: Juvenile ossifying fibroma (JOF) is a rare, benign, fibro-osseous lesion characterized by aggressive growth and potential for recurrence. It primarily affects children and adolescents, with two histopathological subtypes: trabecular JOF (TrJOF) and psammomatoid JOF (PsJOF). TrJOF typically presents in the jaws of younger individuals, often before the age of 15.
View Article and Find Full Text PDFIntegration of Clinical, Radiographic, Histologic, and Molecular Findings to Diagnose Craniofacial Fibrous Dysplasia.
J Craniofac Surg
April 2025
Division of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia.
Fibrous dysplasia (FD) is a benign bone tumor consisting of fibrotic deposits interwoven with disorganized bone. Craniofacial FD is characterized by progressive expansile overgrowth resulting in facial disfigurement, vision loss, jaw disfunction, and pain. Diagnosis is often made by clinical presentation and suggestive radiographic findings, with histologic and genetic analyses recommended in questionable cases.
View Article and Find Full Text PDFSculpting Solutions: A Case Report of Resection and Reconstruction in an Aggressive Mandibular Juvenile Ossifying Fibroma and Review of Literature.
Cureus
February 2025
Department of Oral and Maxillofacial Surgery, Jagadguru Sri Shivarathreeshwara (JSS) Dental College and Hospital, Mysuru, IND.
Juvenile ossifying fibroma (JOF) is a rare, benign, yet locally aggressive fibro-osseous lesion that primarily affects children and adolescents. This case report describes a 10-year-old female patient presenting with a three-month history of progressive swelling on the right lower third of her face, accompanied by trismus. Clinical examination revealed a firm, non-tender swelling extending from the right corner of the mouth to the angle of the mandible, with buccal cortical expansion and vestibular tenderness near the mandibular right second molar.
View Article and Find Full Text PDFA Case of Juvenile Trabecular Ossifying Fibroma Arising from the Maxilla in a 2-Year-Old Child.
Yonago Acta Med
February 2025
Division of Oral and Maxillofacial Surgery, Department of Sensory and Motor of Organs, School of Medicine, Faculty of Medicine, Tottori University, Yonago 683-8503, Japan.
An ossifying fibroma is a fibroosseous lesion from the maxilla and mandible. Its histopathological subtypes include juvenile trabecular ossifying fibroma (JTOF) and juvenile psammomatoid ossifying fibroma. It commonly affects young individuals and is invasive in nature.
View Article and Find Full Text PDFClassification of Fibro-Osseous Tumors in the Craniofacial Bones Using DNA Methylation and Copy Number Alterations.
Mod Pathol
June 2025
Department of Pathology and Medical Biology, University Medical Center Groningen, Groningen, the Netherlands; Department of Pathology, Amsterdam University Medical Center, Amsterdam, the Netherlands. Electronic address:
Fibro-osseous tumors of the craniofacial bones are a heterogeneous group of lesions comprising cemento-osseous dysplasia (COD), cemento-ossifying fibroma (COF), juvenile trabecular ossifying fibroma (JTOF), psammomatoid ossifying fibroma (PsOF), fibrous dysplasia (FD), and low-grade osteosarcoma (LGOS) with overlapping clinicopathological features. However, their clinical behavior and treatment differ significantly, underlining the need for accurate diagnosis. Molecular diagnostic markers exist for subsets of these tumors, including GNAS mutations in FD, SATB2 fusions in PsOF, mutations involving the RAS-MAPK signaling pathway in COD, and MDM2 amplification in LGOS.
View Article and Find Full Text PDF