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http://dx.doi.org/10.1007/s12033-022-00521-0 | DOI Listing |
Chem Sci
September 2025
Department of Chemical Sciences, Centre for Advanced Functional Material, Indian Institute of Science Education and Research (IISER) Kolkata Mohanpur 741246 India
[This corrects the article DOI: 10.1039/D5SC03783B.].
View Article and Find Full Text PDFBiol Open
September 2025
Departments of Biochemistry & Medical Genetics, University of Manitoba, Winnipeg, R3T 2N2, Canada.
The GM2 gangliosidoses are lysosomal storage disorders exhibiting a spectrum of neurological phenotypes ranging from childhood death to debilitating adult-onset neurological impairment. To date, no mouse model harbouring a specific human mutation causing GM2 gangliosidosis has been created. We used CRISPR/Cas9 to generate knockin (KI) mice with the common adult-onset Hexa Gly269Ser variant as well as knockout (KO) mice with Hexa mutations expected to cause complete HexA deficiency.
View Article and Find Full Text PDFFront Neurosci
August 2025
Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, United States.
[This corrects the article DOI: 10.3389/fnins.2023.
View Article and Find Full Text PDFBiomed Res Int
August 2025
[This corrects the article DOI: 10.1155/2022/4246086.].
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