Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: The objective of this study was to evaluate the accumulation of ions in blood and organs caused by titanium (Ti) metal particles in a mandibular defect in rats, together with a description of the local reaction of oral tissues to this Ti alloy debris.
Methods: Twenty Sprague-Dawley rats were randomly distributed into three groups: an experimental group with a mandibular bone defect filled with metallic debris obtained by implantoplasty; a positive control group; and a negative control group. Thirty days after surgery, the rats were euthanized and perilesional tissue surrounding the mandibular defect was removed, together with the lungs, spleen, liver, and brain. Two blood samples were collected: immediately before surgery and before euthanasia. The perilesional tissue was histologically analyzed using hematoxylin-eosin staining, and Ti, aluminum, and vanadium ion concentrations in blood and organs were measured by TQ-ICP-MS. Descriptive and bivariate analyses of the data were performed.
Results: All rats with implanted metal debris showed metal particles and a bone fracture callus on the osseous defect. The metal particles were surrounded by a foreign body reaction characterized by the presence of histiocytes and multinucleated giant cells (MNGCs). The experimental group had a significant higher concentration of Ti ions in all studied organs except lung tissue (p < 0.05). In addition, there were more V ions in the brain in the experimental group (p = 0.008).
Conclusions: Although further studies are required to confirm the clinical relevance of these results, Ti metal particles in the jaw might increase the concentration of metal ions in vital organs and induce a foreign body reaction.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10087269 | PMC |
| http://dx.doi.org/10.1002/JPER.22-0091 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Tuning the Electronic Structure in the MoS/SrTiO Heterojunction via Phase Evolution of the SrTiO Substrate.
ACS Nano
September 2025
Department of Chemical Physics, Key Laboratory of Precision and Intelligent Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China.
The coupling between transition metal dichalcogenides (TMDCs) and SrTiO has recently emerged as a fertile platform for discovering interfacial phenomena, where particle interactions, lattice coupling, and dielectric screening give rise to interesting physical effects. These hybrid systems hold significant promise for two-dimensional (2D) electronics, ferroelectric state control, and metastable phase engineering. However, effective modulation of the interfacial electronic structure remains a critical challenge.
View Article and Find Full Text PDFHigh Shear Conversion of Elemental Bismuth in Water Under Air to 2D Bismuth Oxycarbonate.
Chemistry
September 2025
Institute for Nanoscale Science and Technology, College of Science and Engineering, Flinders University, Bedford Park, Adelaide, South Australia, 5042, Australia.
2D Bismuth oxycarbonate (2D BOC) nanosheets have a unique layered structure with many applications, including capture and reduction of carbon dioxide. Processing powdered elemental bismuth in water under ambient air conditions using a vortex fluidic device (VFD) results in the formation of 2D BOC without the need of surfactants or other excipients. The induced high shear mechanical energy in the form of micron/submicron topological typhoon like spinning top (ST) fluid flow drives the conversion, which we propose initially melts the metal particles which are spontaneously oxidised at the liquid-quartz tube interface to form 2D bismuth oxide (BiO).
View Article and Find Full Text PDFAdvances in ICP-MS-Based Nanoparticle Characterization: Techniques and Challenges in Biological Sample Analysis.
J Sep Sci
September 2025
Department of Analytical Chemistry, Faculty of Science, Palacký University Olomouc, Olomouc, Czech Republic.
The increasing use of engineered nanoparticles (NPs) in consumer and biomedical products has raised concern over their potential accumulation, transformation, and toxicity in biological systems. Accurate analytical methods are essential to detect, characterize, and quantify NPs in complex biological matrices. Inductively coupled plasma mass spectrometry (ICP-MS) has emerged as a leading technique due to its high sensitivity, elemental selectivity, and quantitative capabilities.
View Article and Find Full Text PDFIntroducing a back filter: the impact of metal type on reducing particulate matter and sulfide emissions from diesel engine exhaust.
Environ Sci Pollut Res Int
September 2025
Department of Chemistry Education, Farhangian University, P.O. Box 14665-889, Tehran, Iran.
This study introduces a back filter installed at the end of the exhaust pipe of city buses. The impact of the metal type used in its construction on the absorption of suspended particles and the reduction of sulfides in diesel engine exhaust gases is investigated. The back filter is constructed from three metals: copper, zinc, and nickel.
View Article and Find Full Text PDFGreen synthesis of silver nanoparticles using Ocimum sanctum for efficient Congo red dye removal: a response surface methodology approach.
Environ Monit Assess
September 2025
Department of Civil Engineering, Faculty of Engineering, Karpagam Academy of Higher Education, Pollachi Main Road, Eachanari Post, Coimbatore, Tamil Nadu, 641021, India.
Synthetic dyes, such as Congo red (CR), pose serious threats to human health and aquatic ecosystems because of their carcinogenicity and resistance to degradation, necessitating the development of efficient and eco-friendly remediation strategies. In this study, silver nanoparticles (AgNPs) were synthesized via a green method using Ocimum sanctum (holy basil) leaf extract and applied for CR dye removal from aqueous solutions. The adsorption process was optimized using response surface methodology (RSM) based on Box-Behnken design (BBD), evaluating the influence of key parameters including pH, AgNP dosage, initial dye concentration, contact time, and temperature.
View Article and Find Full Text PDF