Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objectives: Invasive aspergillosis is a threat for immunocompromised patients. We present a case series of aggressive cerebral vasculitis caused by Aspergillus spp. infection in immunocompromised patients.
Methods: We present a retrospective case series of three autopsy-proven invasive cerebral aspergillosis with diffuse vasculitis affecting large caliber cerebral vessels.
Results: Three patients were immunosuppressed: one on rituximab, one on corticosteroids, and one with a renal transplant. Two of these patients were diagnosed with cerebral aspergillosis on postmortem.
Conclusion: Aspergillus cerebral vasculitis is a rare form of invasive aspergillosis that should be considered in an immunocompromised individual with suggestive lesions on imaging. It should be suspected as a possible cause of aseptic neutrophil meningitis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijid.2022.05.056 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Case Report: A case of neuropsychiatric lupus with primary central nervous system diffuse large B-cell lymphoma.
Front Immunol
September 2025
Department of Rheumatology and Immunology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Background: The coexistence of neuropsychiatric systemic lupus erythematosus (NPSLE) and primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system (CNS) (PCNS DLBCL) is extremely rare in clinical practice. This article retrospectively analyzes the clinical manifestations, imaging examinations, pathological diagnosis, and treatment process of a patient with NPSLE, from the appearance of intracranial abnormal signal shadows to the final diagnosis of PCNS DLBCL.
Case Summary: A 32-year-old Chinese female patient had previously visited our hospital due to vomiting and delirium and was diagnosed with NPSLE.
Risk of Stroke Recurrence Following Isolated Retinal Artery Occlusion Versus Minor Stroke or Transient Ischemic Attack.
Stroke
September 2025
Division of Neurointerventional Surgery, Department of Neurosurgery, University of Maryland Medical Center, Baltimore (H.C., D.G.).
Background: Retinal artery occlusion (RAO) is a form of ischemic stroke per the American Heart Association, yet high-level evidence guiding management and prognostication is limited. The risk of future cerebral infarction following nonarteritic isolated RAO (iRAO; without concomitant cerebral infarction) is unclear. This study compares the risk of stroke recurrence following iRAO versus nondisabling ischemic cerebrovascular events (NICEs), including transient ischemic attacks and minor ischemic strokes.
View Article and Find Full Text PDFPresumed Cerebral Vasculitis Following Pneumococcal Meningitis: A Rare but Life-Threatening Complication.
Case Rep Med
August 2025
Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
A 65-year-old woman presented with pneumococcal sepsis and meningitis. Despite appropriate antimicrobial therapy and intravenous (IV) dexamethasone, her mental status did not improve. Findings of brain imaging were suggestive of cerebral vasculitis.
View Article and Find Full Text PDFConcomitant valve-sparing pulmonic root replacement and valve-sparing aortic root replacement for giant cell arteritis.
Multimed Man Cardiothorac Surg
September 2025
Division of Cardiac Surgery, Department of Surgery, University of Maryland, Baltimore, MD, USA
Concomitant aortic root and pulmonic root aneurysms secondary to giant cell arteritis are extremely rare. We present a case of a patient with giant cell arteritis who underwent concomitant valve-sparing aortic root replacement and valve-sparing pulmonary root replacement along with tricuspid valve repair.
View Article and Find Full Text PDFThe role of calprotectin in giant cell arteritis - from pathophysiology to possible clinical applications.
Front Immunol
August 2025
Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
Giant cell arteritis (GCA) is an immune-mediated vasculitis predominantly affecting individuals aged 50 years and older, with clinical manifestations often overlapping with polymyalgia rheumatica (PMR). Despite advances in imaging and the advent of novel steroid-sparing agents, such as tocilizumab, challenges persist in accurately diagnosing and monitoring disease activity. Traditional inflammatory markers like C-reactive protein and erythrocyte sedimentation rate are frequently limited by their inability to fully capture disease dynamics, especially in patients receiving IL-6 inhibitors.
View Article and Find Full Text PDF