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Genetic mapping of , a pupal lethal mutation in . | LitMetric

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Article Abstract

An EMS mutagenesis screen was conducted in to identify growth control mutants. The multi-institution Fly-CURE consortium phenotypically characterized the mutant using the system which displayed a mutant lethal phenotype with reduced head development, and darkened ocular tissue. Complementation mapping was conducted to identify the affected gene. A failure to complement was identified in , resulting in the identification of the novel allele, is a known disruptor of the cell cycle and our data are consistent with early larval/embryonic lethality displayed in numerous species.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012533PMC
http://dx.doi.org/10.17912/micropub.biology.000542DOI Listing

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