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Studies of dyadic interaction often examine infants' social exchanges with their caregivers in settings that constrain their physical properties (e.g., infant posture, fixed seating location for infants and adults). Methodological decisions about the physical arrangements of interaction, however, may limit our ability to understand how posture and position shape them. Here we focused on these embodied properties of dyadic interaction in the context of object play. We followed 30 mother-infant dyads across the first year of life (at 3, 6, 9, and 12 months) and observed them during 5 min of play with a standard set of toys. Using an interval-based coding system, we measured developmental change in infant posture, how mothers and infants positioned themselves relative to one another, and how they populated interaction spaces with objects. Results showed that mother-infant dyads co-constructed interaction spaces and that the contributions of each partner changed across development. Dyads progressively adopted a broader spatial co-orientation during play (e.g., positioned at right angles) across the first year. Moreover, advances in infants' postural skills, particularly increases in the use of independent sitting in real time, uniquely predicted change in dyadic co-orientation and infants' actions with objects, independent of age. Taken together, we show that the embodied properties of dyadic object play help determine how interactions are physically organized and unfold, both in real time and across the first year of life.
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http://dx.doi.org/10.1111/desc.13281 | DOI Listing |
Med Eng Phys
October 2025
Department of Engineering Science, University of Oxford, United Kingdom. Electronic address:
Traditionally, clinical devices are designed, tested and improved through lengthy and expensive laboratory experiments and clinical trials [1]. More recently, computational methods have allowed for rapid testing, speeding up the design process and enabling far more complete searches of design space. While computational models cannot fully capture the complexities of biological systems, they provide valuable insights into crucial underlying mechanisms, such as the effects of fluid-structure interactions (FSIs).
View Article and Find Full Text PDFJ Aging Phys Act
September 2025
Occupational Therapy Department, Monash University, Frankston, VIC, Australia.
Background/objective: Adherence rates to supervised gym-based exercise programs traditionally decline over time, highlighting the need to understand participants' perceptions regarding barriers and facilitators to long-term participation. To explore the experiences of people with one or more chronic conditions participating in an ongoing, supervised, gym-based exercise program in regional Australia.
Method: Semistructured interviews were completed with 40 participants and were analyzed thematically using a descriptive qualitative approach.
Biochim Biophys Acta Mol Cell Biol Lipids
September 2025
Department of Biochemistry and Molecular Biology, Faculty of Biology, Complutense University, Madrid, Spain; Department of Biochemistry and Molecular Biology, Faculty of Chemistry, Complutense University, Madrid, Spain; Research Institute "Hospital 12 de Octubre (imas12)", Madrid, Spain. Electronic
Pulmonary surfactant protein C (SP-C) may play a key role in alveolar homeostasis by modulating vesicle uptake in alveolar cells. This study explores how SP-C regulates internalization of model unilamellar lipid vesicles by type II alveolar epithelial cells (AECII) and alveolar macrophages (AMϕ), focusing on the effect of lipid composition, palmitoylation state, and interactions with external stimuli like lipopolysaccharides (LPS) or the other hydrophobic surfactant protein SP-B. Using fluorescence-based techniques, we demonstrated that SP-C enhances vesicle uptake in a lipid-dependent manner.
View Article and Find Full Text PDFGesundheitswesen
September 2025
Klinik für Rehabilitations- und Sportmedizin, Medizinische Hochschule Hannover, Hannover, Deutschland.
The study addresses the gap in rehabilitation care of people with cognitive and/or multiple Impairments. Conventional medical care structures are often insufficiently adapted to the needs of this patient group. In this project, the rehabilitative care gap is practically closed with a social space-oriented rehabilitation concept for people with cognitive and/or multiple Impairments and to create sustainable solutions.
View Article and Find Full Text PDFJ Colloid Interface Sci
August 2025
Research Centre of Ecology & Environment for Coastal Area and Deep Sea, Guangdong University of Technology, Guangzhou 510006, China; Guangdong Basic Research Center of Excellence for Ecological Security and Green Development, Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou),
Hypothesis: Gas hydrate formation in sediments is influenced by the availability of gas-water interfacial areas, which governs gas-water interactions. The surface wettability of sediment particles is expected to affect the spatial distribution of water within the pore space, thereby altering the extent of gas-liquid contact. Consequently, by tuning the wettability heterogeneity of the sediment, the spatial distribution of pore water can be regulated, which in turn influences the gas-water interactions and the kinetics of gas hydrate formation.
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