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Goal: Assessing barriers to vaccination among healthcare workers may be particularly important given their roles in their respective communities. We conducted a mixed methods study to explore healthcare worker perspectives on receiving COVID-19 vaccines at a large multisite academic medical center.
Methods: A total of 5,917 employees completed the COVID-19 vaccine confidence survey (20% response rate). Most participants were vaccinated (93%). Compared to vaccinated participants, unvaccinated participants were younger (60% < 44 years), more likely to be from a non-Asian minority group (48%), and more likely to be nonclinical employees (57% vs. 46%). Among the unvaccinated respondents, 53% indicated they would be influenced by their healthcare provider, while 19% reported that nothing would influence them to get vaccinated. Key perceived barriers to vaccination from the qualitative analysis included the need for more long-term safety and efficacy data, a belief in the right to make an individual choice, mistrust, a desire for greater public health information, personal health concerns, circumstances such as prior COVID-19 infection, and access issues.
Principal Findings: Strategies endorsed by some participants to address their concerns about safety and access included a communication campaign, personalized medicine approaches (e.g., individual appointments to discuss how the vaccine might interact with personal health conditions), and days off to recover. Mistrust and a belief in the right to make an individual choice may be harder barriers to overcome; further dialogue is needed.
Applications To Practice: These findings reflect potential strategies for vaccine requirements that healthcare organizations can implement to enhance vaccine confidence. In addition, organizations can ask respected health professionals to serve as spokespeople, which may help shift the perspectives of unvaccinated healthcare workers.
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http://dx.doi.org/10.1097/JHM-D-21-00226 | DOI Listing |
Nat Hum Behav
September 2025
Institut Jean Nicod, Département d'Études Cognitives, École Normale Supérieure, Université PSL, EHESS, CNRS, Paris, France.
School interventions targeting adolescents' general knowledge of vaccination are rare despite their potential to reduce vaccine hesitancy. This cluster-randomized trial involving 8,589 French ninth graders from 399 schools tests two interventions against the standard curriculum. The first provided teachers with ready-to-use pedagogical activities, while the second used a chatbot.
View Article and Find Full Text PDFVaccine
September 2025
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Background: Among pregnant and postpartum women, decision-making for receiving the COVID-19 vaccine is influenced by vaccine safety concerns, misconceptions, shifting vaccine policies, and exclusion in the initial vaccine rollout. This caused confusion and vaccine hesitancy among many groups including pregnant and postpartum women.
Objective: The objective of this study was to understand the multilevel factors that influence vaccine decision-making among pregnant and postpartum women in Pakistan, which is crucial for improving vaccine demand among the vulnerable group-pregnant and postpartum women.
Vaccine
September 2025
School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region; Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Park, Hong Kong, SAR, China; The State Key Laboratory of Brain and Cognitive Sciences, The University of H
Background: Vaccine confidence is crucial for achieving high vaccination rates against COVID-19, yet vaccine confidence varied significantly throughout the pandemic. This study assessed the trajectories and predictors of COVID-19 vaccine confidence from prior to the vaccine rollout to mass vaccination.
Methods: It is a population-based cohort study with nine waves of longitudinal data from September 2020 to February 2023, spanning the pre-vaccine rollout to COVID-19 mass vaccination in Hong Kong.
JMIR Public Health Surveill
September 2025
Center of Indigenous Health Care, Department of Community Health, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan.
Background: The COVID-19 pandemic has devastated economies and strained health care systems worldwide. Vaccination is crucial for outbreak control, but disparities persist between and within countries. In Taiwan, certain indigenous regions show lower vaccination rates, prompting comprehensive inquiries.
View Article and Find Full Text PDFEpidemiol Serv Saude
September 2025
Instituto Aggeu Magalhães, Fundação Oswaldo Cruz, Recife, PE, Brazil.
Objective: To estimate the incidence and factors associated with SARS-CoV-2 reinfection and post-vaccination infection in nursing professionals.
Methods: This was a prospective, descriptive, and analytical cohort study conducted in Recife from March 2020 to January 2023, following 399 nursing professionals. The cumulative incidences of COVID-19 infection and reinfection were estimated with a 95% confidence interval (95%CI).