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http://dx.doi.org/10.1001/jama.2022.4302 | DOI Listing |
Breast J
September 2025
University of Hawai'i Cancer Center, Honolulu, Hawaii, USA.
The Oncotype DX test is standardly used for patients with early-stage, hormone-receptor-positive, HER2-negative breast cancers to determine the benefit from chemotherapy and the likelihood of distant recurrence. The relationship between Oncotype DX recurrence scores and race/ethnicity is still being studied. This retrospective study aims to evaluate the relationship between Oncotype DX recurrence scores, race/ethnicity, and clinicopathological factors and to support the applicability of the Oncotype DX test for a diverse breast cancer population of Hawaii.
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August 2025
Department of Surgery, Hebei Medical University, Shijiazhuang, Hebei, China.
Background: Tumor deposit (TD) is an independent risk factor associated with recurrence or metastasis for patients with colorectal cancer (CRC). The scenario in which both TD and lymph node metastasis (LNM) are positive is not clearly illustrated by the current TNM staging system. Simply treating one TD as one or two LNMs by a weighting factor is inappropriate.
View Article and Find Full Text PDFPEC Innov
June 2025
Department of Obstetrics, & Reproductive Science, University of Pittsburgh School of Medicine, Gynecology Pittsburgh, PA, USA.
Objectives: To explore the perceptions of pregnant patients who use substances regarding positive or negative clinician communication during obstetrical care.
Methods: We analyzed qualitative data from 85 semi-structured interviews with pregnant patients who reported or tested positive for substance use, which explored their interaction with obstetric providers during their first prenatal visit. This analysis focuses on patients' perceptions of negative versus positive clinician communication behaviors.
Front Public Health
September 2025
Department of Health Sciences, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Objective: Saudi Arabia has one of the highest prevalences of obesity worldwide, and excessive consumption of sweetened soft drinks significantly contributes to this. In this study, we investigated the patterns of soft drink consumption among Saudi women and identified the socio-demographic and attitudinal factors influencing these patterns.
Design: We studied 1,555 Saudi women aged 20-60 years between October 2022 and March 2023.
Front Public Health
September 2025
School of Sports Training, Chengdu Sports University, Chengdu, Sichuan, China.
Objective: To explore the relationship that mindfulness and life satisfaction have in the process of alleviating depression through physical activity in Chinese universities and the mediating role of life satisfaction and mindfulness in this process.
Methods: Participants were 508 college students (240 males, 268 females, mean age 19.90, SD = ±1.