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http://dx.doi.org/10.3389/fsurg.2022.866191 | DOI Listing |
Biomedicines
August 2025
Department of Gastroenterology, St Mark's National Bowel Hospital & Academic Institute, London NW10 7NS, UK.
Anti-tumour necrosis factor (anti-TNF) medications were historically commonly prescribed as the first-line biologic treatment for chronic inflammatory pouch conditions. However, their use in these conditions is mainly based on retrospective studies of relatively small numbers of patients with short follow up periods. We aimed to describe the long-term outcomes of first-line anti-TNF therapy in a large, multi-centre, multi-national patient cohort with chronic inflammatory pouch conditions.
View Article and Find Full Text PDFBMC Gastroenterol
July 2025
Division of Colorectal Surgery, National University Hospital, NUHS Tower Block, Level 8, 1E Kent Ridge Road, Singapore, 119228, Singapore.
Background: A defunctioning ileostomy is frequently created to avert the implications of a colo-rectal anastomotic dehiscence in rectal cancer surgery. The timing of closure of the ileostomy remains debatable as it is believed that early closure (EC) may be beneficial to most patients than the standard practice of late closure (LC). This meta-analysis was performed to compare surgical outcomes in patients who underwent EC versus LC.
View Article and Find Full Text PDFColorectal Dis
June 2025
University College London, London, UK.
Aim: To compare current UK surgical practice against evidence-based anastomotic evaluation techniques prior to ileostomy closure.
Methods: An online survey was distributed to UK consultant colorectal surgeons with Association of Coloproctology of Great Britain and Ireland affiliation to assess preoperative investigations. Data were collected at two timepoints: 2019 and 2024.
Turk J Surg
May 2025
Department of Colorectal Surgery, The Alfred, Melbourne, Australia.
Natural orifice specimen extraction surgery (NOSE) is an extension of minimally invasive colorectal surgery. NOSE was introduced into the unit in January 2024 in selected group of patients. The aim of this study was to evaluate the initial experience of NOSE surgery in minimally invasive surgery colorectal surgery in terms of feasibility and safety outcomes.
View Article and Find Full Text PDFUpdates Surg
June 2025
Colorectal Surgery Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy.
In our previous survey of experts, surgeon's decision-making process (DMP) about protective ileostomy (PI) creation after anterior resection was investigated. Based on our previous data, a multiple choice questionnaire has been developed. The aim is to perform a quantitative analysis of the results obtained from an international survey and to describe the clinical practice worldwide.
View Article and Find Full Text PDF