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Context: Sex differences influence symptom presentations after sport-related concussion and may be a risk factor for certain concussion clinical profiles.
Objective: To examine sex differences on the Concussion Clinical Profile Screen (CP Screen) in adolescents after sport-related concussion.
Design: Cross-sectional study.
Setting: A concussion specialty clinic.
Patients Or Other Participants: A total of 276 adolescent (age = 15.02 ± 1.43 years; girls = 152 [55%]) athletes with a recently diagnosed concussion (≤30 days).
Main Outcome Measure(s): The 5 CP Screen profiles (anxiety mood, cognitive fatigue, migraine, vestibular, ocular) and 2 modifiers (neck, sleep), symptom total, and symptom severity scores were compared using a series of Mann-Whitney U tests between boys and girls.
Results: Girls (n = 152) scored higher than boys (n = 124) on the cognitive fatigue (U = 7160.50, z = -3.46, P = .001) and anxiety mood (U = 7059, z = -3.62, P < .001) factors but not on the migraine (U = 7768, z = -2.52, P = .01) factor. Girls also endorsed a greater number of symptoms (n = 124; U = 27233, z = -3.33, P = .001) and scored higher in symptom severity (U = 7049, z = -3.60, P < .001) than boys.
Conclusions: Among adolescents, symptom endorsement on the CP Screen varied based on sex, and clinicians need to be aware of these differences, especially when evaluating postconcussion presentation in the absence of baseline data.
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http://dx.doi.org/10.4085/1062-6050-0670.21 | DOI Listing |
Lipids Health Dis
September 2025
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Background: The CRP-albumin-lymphocyte (CALLY) index has potential clinical value as a novel marker integrating inflammatory, nutritional and immune status in the development of colorectal polyps. This study examined whether gender factors influence the association between CALLY and colorectal polyps; in addition to elucidating whether metabolic pathways mediate this relationship.
Methods: This is a cross-sectional study including 5409 adult health screening participants who completed colonoscopy.
BMC Endocr Disord
September 2025
Internal Medicine Department, Faculty of Medicine, Beni-Suef University, Beni-Suef City, 62514, Egypt.
Background: Thyroid nodules (TNs) are frequent and often benign. Accurately differentiating between benign and malignant nodules is crucial for proper management. This research aims to use ultrasonography to examine TNs and identify possible risk factors in order to improve patient outcomes and diagnostic accuracy.
View Article and Find Full Text PDFAlzheimers Dement
September 2025
Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Introduction: Mild cognitive impairment (MCI) represents a transitional stage between normal aging and dementia. We investigate associations among cardiovascular and metabolic disorders (hypertension, diabetes mellitus, and hyperlipidemia) and diagnosis (normal; amnestic [aMCI]; and non-amnestic [naMCI]).
Methods: Multinomial logistic regressions of participant data (N = 8737; age = 70.
Sci Rep
September 2025
Paleoanthropology Section, Department of Geosciences, Institute for Archaeological Sciences, University of Tübingen, Tübingen, Germany.
Human communication is remarkable for its flexibility, a trait largely reflected in its multimodal nature and shared to some extent with nonhuman primates. Although individual differences in social behaviour are known to have evolutionary implications, their role in shaping primate communication remains largely unexplored. This study adopts a multimodal framework to partition variation in chimpanzees' use of multicomponent and multisensory communicative strategies into socio-environmental, between-individual, and within-individual sources.
View Article and Find Full Text PDFInt Psychogeriatr
September 2025
Department of Psychology and Neuroscience, Temple University, Philadelphia, PA, United States. Electronic address:
Background: As demand for mental healthcare access grows among older adult populations, digital mental health tools have emerged as promising tools. However, bridging the digital divide among older technology users remains critical. This post-hoc analysis evaluated potential factors influencing the adoption of a digital mental health tool in older adults.
View Article and Find Full Text PDF