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Background: Work stress is a serious problem in primary education. Decades of research underline the importance of participatory, organizational-level work stress prevention approaches. In this approach, measures are planned to tackle causes of work stress in a participatory manner and implemented by a working group consisting of members of the organization. This approach can only be effective if the measures contain effective ingredients to decrease work stress risks and are successfully implemented. The aim of this paper is to present an outline of a work stress prevention approach that is evaluated in primary education. To ensure the appropriateness of measures, a logic model of change is built as part of the risk assessment to facilitate the selection of appropriate measures. Progression on target behaviors as well as implementation factors are real-time monitored during implementation and fed back to the working groups, to provide the opportunity to adjust action plans when needed to optimize implementation.
Methods: The approach consists of five steps: (1) : installing an advisory board and working groups, (2) : inventory of work stress risks (questionnaires and focus groups). In addition, a behavioral analysis is performed to build a logic model of change to facilitate selection of measures, (3) : conducting an action plan with appropriate measures (focus groups), (4) : implementing the action plan. During implementation progression on target behaviors and implementation factors are monthly monitored and fed back to the working groups, and (5) : effects of the approach are studied in a controlled trial with measurements at baseline (T0), 1 year (T1), and 2 years (T2) follow-up. A process evaluation is carried out using quantitative (questionnaires and real-time monitoring data) and qualitative (interviews and data logs) data to study the implementation process of all steps of the work stress approach.
Discussion: We believe that building a logic model of change and real-time monitoring of implementation could be of added value to improve the success of the work stress prevention approach. With this study, we aim to provide more insights into work stress intervention research, especially in primary education.
Clinical Trial Registration: The study is registered in Netherlands Trial Register (ClinicalTrials.gov #NL9797, October 18, 2021).
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http://dx.doi.org/10.3389/fpsyg.2022.827278 | DOI Listing |
Acc Chem Res
September 2025
Departamento de Química, Universidad Autónoma Metropolitana-Iztapalapa, Ave. Ferrocarril San Rafael Atlixco 186, Col. Leyes de Reforma 1A sección, Alcaldía Iztapalapa, 09310 Mexico City, Mexico.
ConspectusWhat does the word antioxidant mean? Antioxidants are supposed to be nontoxic, versatile molecules capable of counteracting the damaging effects of oxidative stress (OS). Thus, when evaluating a candidate molecule as an antioxidant, several aspects should be considered. Antioxidants are more than free radical scavengers.
View Article and Find Full Text PDFMol Pharm
September 2025
Department of Biochemical Engineering, University College London, Gower Street, London, WC1E 6BT, U.K.
We built a custom device to subject an antibody fragment A33 Fab to controlled stress conditions that combined pH, temperature, agitation, and LED-based light exposure in polypropylene microplates; to simulate the real-world challenges it may encounter during storage and transportation and to evaluate the key degradation routes in Fab formulations. We also explored the addition of Tween 80 as a surfactant and the impact of plate surface siliconisation. Monomer loss and fragmentation was monitored by size-exclusion chromatography, aggregate formation determined by changes in hydrodynamic radius in DLS, and chemical modifications identified through intact mass analysis by LC-MS, and N-terminal sequencing.
View Article and Find Full Text PDFNeuroscience
August 2025
Department of Biology, Utah State University, Logan, UT, United States. Electronic address:
Forming social bonds is fundamental in helping us foster connections with others. The loss of a loved one often results in grief, stress, and loneliness, and the stress response system of the body has been implicated in the physiological symptoms associated with grieving. Corticotropin releasing factor (CRF) is the hormone that initiates the stress response in the body and acts at two different receptor subtypes CRF receptor (CRFR)1 and CRFR2.
View Article and Find Full Text PDFSangyo Eiseigaku Zasshi
September 2025
Purpose: This study aimed to obtain useful suggestions and findings regarding IT engineers' stressors, their structures, and the process of recognizing stress, which are useful for workplace environmental improvement activities as a primary prevention of mental illness.
Methods: Data were collected through interviews conducted with 15 employees from Information Systems departments and System Integration Service Providers and analyzed qualitatively using the modified grounded theory approach.
Results: The qualitative analysis generated 27 concepts, 13 categories, and five category groups.
Sangyo Eiseigaku Zasshi
September 2025
School of Health Sciences, Faculty of Nursing, Fujita Health University.
Objectives: Despite efforts to promote mental health in the workplace, employee mental health challenges continue to increase. Organizations continue to face significant challenges to support employees in safely returning to work after mental health-related leaves and to ensure long-term stability without relapse. This literature-based study was performed to clarify support skills that occupational health nurses employ to facilitate return to work for employees with mental health issues.
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