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A composite T cell biomarker in pre-treatment blood samples correlates with detection of immune-related adverse events. | LitMetric

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Article Abstract

Finding biomarkers for predicting anti-tumor responses and immune-related adverse events (irAEs) with immune checkpoint therapy remains a challenge. Lozano et al. have developed a composite biomarker score that includes the frequency of effector-memory CD4 T cells and TCR clonality of CD4 T cells in peripheral blood as a potentially predictive biomarker of irAEs.

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http://dx.doi.org/10.1016/j.ccell.2022.02.015DOI Listing

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