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Background: Toxoplasma gondii and Neospora caninum infections in primates are potentially fatal and directly impact the conservation of these animals and public health.
Materials And Methods: A total of 38 blood/clot samples collected from free-living and captive neotropical primates undergoing clinical care or found dead by environmental authorities in the Mato Grosso State, Brazil, were analyzed by PCR for DNA detection of T. gondii and N. caninum. Furthermore, eight animals were submitted to immunohistochemistry for the detection of T. gondii.
Results: DNA of T. gondii and N. caninum was amplified in 11 (28.95%) 10 (26.32%) of samples analyzed, respectively. Coinfection was observed in three individuals. One animal returned a positive result in the immunohistochemistry for the detection of T. gondii.
Conclusion: These findings reflect a concern for the conservation of these animals, as the pathogen-host interaction is unpredictable and infections by these protozoa can lead to animal mortality, which has a substantial impact on endangered species.
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http://dx.doi.org/10.1111/jmp.12575 | DOI Listing |
mSphere
September 2025
Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
Apicomplexan AP2 (ApiAP2) family proteins are a family of transcription factors that are known to regulate gene expression in apicomplexan pathogens, including . In this study, we focused on TgAP2X-7, a member of the APiAP2 family that is predicted to be essential for fitness. Endogenous tagging of TgAP2X-7 followed by immunofluorescence analysis revealed that it's a cell cycle-regulated nuclear protein with peak expression in the G1 phase.
View Article and Find Full Text PDFParasitol Int
September 2025
Immunoparasitology Laboratory, Faculty of Veterinary Science-La Plata National University, La Plata, 1900 Buenos Aires, Argentina; National Scientific and Technical Research Council (CONICET), Ciudad Autónoma de Buenos Aires (C1425FQB), Argentina; Institute of Parasitology, University of Bern, Län
The apicomplexan protozoa Neospora caninum, Sarcocystis spp. and Toxoplasma gondii are worldwide distributed. Goat infections with these protozoans are frequent, although the relationship with milk production is unknown.
View Article and Find Full Text PDFActa Trop
September 2025
Department of Public Health, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.
Congenital toxoplasmosis (CT) due to Toxoplasma gondii, an apicomplexan parasite, leads to significant sequelae in children, foetal losses and neonatal deaths worldwide. This study aimed to assess the burden of CT in Burundi for the year 2020. We used epidemiological and economic data collected in major hospitals in Burundi, the Ministry of Public Health in Burundi and international peer-reviewed literature to estimate the disability-adjusted life years (DALYs) and economic costs spent on prenatal consultations, diagnosis and treatment of toxoplasmosis for pregnant women.
View Article and Find Full Text PDFExp Parasitol
September 2025
Institute of Parasitology, Faculty of Veterinary Medicine, Leipzig University, Leipzig, Germany; Tifton Veterinary Diagnostic and Investigational Laboratory and Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Tifton, USA. Electronic address: berit.bangoura@u
The common parasite Toxoplasma gondii can infect all warm-blooded animals, including humans. Although most infections in humans remain asymptomatic, clinical toxoplasmosis can develop into a fatal disease. Infections are usually contracted by oral ingestion of tissue cysts or oocysts contained in cat feces.
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