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Allura red (AR) is a member of azo dyes is commonly used as an additive in foods and soft drinks. However, due to the special harm of the azo structure to the human body, the dosage control of AR becomes particularly necessary. The present detection methods are time-consuming, expensive and complicated. In order to address the above issues, a core-shell nanocubes constructed sensor has been developed to determine the ultrawide detection range and selective recognition of AR with a long-term reusability. The core-shell architecture is composed of carbon material of 12.64 nm thickness covering 600 nm MnO nanocube. This nanocomposite combines the advantages of MnO@C, possessing high electrocatalysis and chemical stability. As confirmed in using sports drinks as real samples, the as-prepared AR sensor exhibites excellent selectivity with an ultra-wide linear range from 0.1 to 1748.4 μM, and meanwhile, this sensor can also meet the requirements of remarkable anti-interference and reusability over 30 days.
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http://dx.doi.org/10.1016/j.fct.2022.112908 | DOI Listing |
J Food Sci
August 2025
Group of Functionality and Ecology of Beneficial Microorganisms (MicroHealth), Dairy Research Institute of Asturias (IPLA-CSIC), Oviedo, Asturias, Spain.
This work addresses in vitro the potential impact of two food additives in the safety spotlight, i.e., the flavor enhancer monosodium glutamate (MSG) and the azo-dye colorant allura red AC (AR), on the human gut microbiota from healthy donors by using in vitro faecal batch culture models, and an intestinal cell line model.
View Article and Find Full Text PDFMol Pharm
September 2025
Drug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki FI-00014, Finland.
Food additives are chemical substances that are added to processed food to improve its flavor, texture, or appearance. Food additives can inhibit intestinal transporters, such as breast cancer resistance protein (BCRP), multidrug resistance associated protein 2 (MRP2), organic anion transporting polypeptide 2B1 (OATP2B1), and P-glycoprotein (P-gp). This inhibition could potentially affect the absorption of their substrate drugs and cause unwanted food-drug interactions.
View Article and Find Full Text PDFInt J Biol Macromol
August 2025
Research Group on Adsorptive and Catalytic Process Engineering (ENGEPAC), Federal University of Santa Maria, Av. Roraima, 1000-7, 97105-900 Santa Maria, RS, Brazil. Electronic address:
This work investigated the effect of structural characteristics of five food dyes on adsorption onto chitosan-based biopolymeric sponges, using statistical physics models, experimental results, and FT-IR analyses to propose a detailed adsorption mechanism. Statistical physics models showed high predictive capacity. The multilayer model was the most effective for predicting the adsorption isotherms of the Indigo carmine, Allura red, and Amaranth.
View Article and Find Full Text PDFToxicol Lett
August 2025
Toxicology and Pharmacology Laboratory, Department of Biotechnology, Faculty of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu District, Tamil Nadu 603203, India. Electronic address:
For centuries, the practice of adding color to food has become deeply ingrained in culinary traditions, evolving into an indispensable aspect of food production today. Major food manufacturing companies extensively use colorants to enhance the visual appeal of their products. However, recent years have seen an increasing number of studies by researchers who have uncovered various health risks associated with food color additives.
View Article and Find Full Text PDFMikrochim Acta
April 2025
Department of Chemistry, Panjab University, Chandigarh, 160014, India.
A sulfonamide derivative synthesized from 1,8-naphthalimide-based amine and 4-methoxy-benzenesulfonyl chloride has been enwrapped into the micelles of a neutral surfactant TX-100 to form highly emissive nanomicelles MXL@TX- 100. The proposed sensor offered highly sensitive turn-off detection of Allura red (linear range = 0.66-224 µM) with the limit of detection (LOD) of 0.
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