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The rate of collision and the relative velocities of the colliding particles in turbulent flows are a crucial part of several natural phenomena, e.g. rain formation in warm clouds and planetesimal formation in protoplanetary discs. The particles are often modelled as passive, but heavy and inertial. Within this model, large relative velocities emerge due to formation of singularities (caustics) of the gradient matrix of the velocities of the particles. Using extensive direct numerical simulations of heavy particles in both two (direct and inverse cascade) and three-dimensional turbulent flows, we calculate the rate of formation of caustics, [Formula: see text] as a function of the Stokes number ([Formula: see text]). The best approximation to our data is [Formula: see text], in the limit [Formula: see text] where [Formula: see text] is a non-universal constant. This article is part of the theme issue 'Scaling the turbulence edifice (part 2)'.
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http://dx.doi.org/10.1098/rsta.2021.0086 | DOI Listing |
World J Urol
September 2025
Bichat Claude Bernard Hospital, Public Assistance of Paris Hospitals, Paris, France.
Purpose: Screening and diagnosing ISUP ≥ 2 prostate cancer is challenging. This study aimed to determine whether canine detection could be beneficial addition to the ISUP ≥ 2 prostate cancer diagnostic protocol by creating a decision-making algorithm for men with suspected prostate cancer.
Methods: We conducted a prospective study at two urology institutions and a French veterinary school, including men with a suspicion of prostate cancer from November to April 2023, which were divided into two groups according to their prostate biopsy results.
PLoS One
September 2025
School of Computer Science, CHART Laboratory, University of Nottingham, Nottingham, United Kingdom.
Background And Objective: Male fertility assessment through sperm morphology analysis remains a critical component of reproductive health evaluation, as abnormal sperm morphology is strongly correlated with reduced fertility rates and poor assisted reproductive technology outcomes. Traditional manual analysis performed by embryologists is time-intensive, subjective, and prone to significant inter-observer variability, with studies reporting up to 40% disagreement between expert evaluators. This research presents a novel deep learning framework combining Convolutional Block Attention Module (CBAM) with ResNet50 architecture and advanced deep feature engineering (DFE) techniques for automated, objective sperm morphology classification.
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September 2025
Hunan Mingxiang Aviation Technology Co., Ltd., Changsha, Hunan, China.
Flexible spacecraft possess the ability to adapt to complex environments and use energy more efficiently, offering enhanced flexibility and stability in space missions, particularly in tasks with significant external disturbances such as deep space exploration and satellite attitude control. However, vibration suppression in flexible spacecraft remains a critical challenge. This study addresses the problem of vibration suppression in flexible spacecraft systems under external disturbances and input constraints.
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September 2025
Remiza AI, Poughkeepsie, New York, United States of America.
Background: Hybrid entertainment formats combining competitive and comedic elements present opportunities to investigate factors driving audience engagement. I analyzed Taskmaster UK (2015-2023), a BAFTA-winning comedy panel show where comedians compete in creative tasks judged by a host, to quantify relationships between scoring mechanics, performer characteristics, and viewer ratings.
Methods: I analyzed 154 episodes encompassing 917 tasks performed by 90 contestants, with audience reception measured through 32,607 IMDb votes.
PLoS Comput Biol
September 2025
Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.
Fanconi Anemia (FA) is a heritable syndrome characterized by DNA damage repair deficits, frequent malformations and a significantly elevated risk of bone marrow failure, leukemia, and mucosal head and neck squamous cell carcinomas (HNSCC). Hematopoietic stem cell gene therapy can prevent marrow failure and lower leukemia risk, but mucosal gene therapy to lower HNSCC risk remains untested. Major knowledge gaps include an incomplete understanding of how rapidly gene-corrected cellular lineages could spread through the oral epithelium, and which delivery parameters are critical for ensuring efficient gene correction.
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