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Background: As a novel and deadly acute respiratory syndrome, which later became known as coronavirus disease 2019 (COVID-19), spread beyond China in late January 2020, there were no laboratories in Africa that could test for the disease. However, in early March, just over a month later, 42 African countries had developed the expertise and resources to perform COVID-19 testing. Our goal was to document this public health success story, learn from it, and use it to inform future public health action.
Intervention: Three groups were primarily responsible for establishing COVID-19 testing capacity in Africa. The first group comprised early test manufacturers who reacted with incredible speed and ingenuity early in the pandemic, such as the German company TIB MolBiol that developed a molecular test for COVID-19 the SARS-CoV-2 genome sequence was available. The second group included private and public donors such as the Jack Ma Foundation, and the last were the coordinators of the rollout, such as the World Health Organization and the Africa Centres for Disease Control and Prevention (CDC).
Lessons Learnt: The first lesson was that speed is critical, especially during a crisis. It was also demonstrated that being a predictable and transparent trusted institution opens doors and improves effectiveness. Africa CDC, which was only three years old, was able to secure significant resources from external partners and rapidly build substantial testing capacity within Africa because it is a trusted institution.
Recommendations: Low- and middle-income countries must build local trusted institutions to better prepare for public health challenges.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689357 | PMC |
http://dx.doi.org/10.4102/ajlm.v10i1.1457 | DOI Listing |
Health Soc Care Deliv Res
September 2025
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Background: Remote services (in which the patient and staff member are not physically colocated) and digital services (in which a patient encounter is digitally mediated in some way) were introduced extensively when the COVID-19 pandemic began in 2020. We undertook a longitudinal qualitative study of the introduction, embedding, evolution and abandonment of remote and digital innovations in United Kingdom general practice. This synoptic paper summarises study design, methods, key findings, outputs and impacts to date.
View Article and Find Full Text PDFEur J Pediatr
September 2025
Neonatal and Pediatric Intensive Care Unit, Intermediate Care Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, 16147, Genoa, Italy.
Unlabelled: Benign Acute Childhood Myositis (BACM) is a transient, self-limiting muscular condition that typically follows viral infections, especially influenza. The COVID-19 pandemic disrupted the circulation of respiratory viruses, altering the epidemiology of related post-infectious complications. This study investigates trends in BACM incidence, clinical features, and viral etiology before and after the pandemic.
View Article and Find Full Text PDFTracking known influenza-like illnesses, such as influenza, is an important problem in public health and clinical medicine. The problem is complicated by the clinical similarity and co-occurrence of many of these illnesses. Additionally, detecting a new or reemergent disease, such as COVID-19, is of paramount importance as recent history has shown.
View Article and Find Full Text PDFInt J Infect Dis
September 2025
Department of Clinical Science, Bergen Integrated Diagnostic Stewardship Cluster, Faculty of Medicine, University of Bergen, Bergen, Norway; Department of Microbiology, Haukeland University Hospital, Bergen, Norway. Electronic address:
Community-acquired pneumonia [CAP] is a leading cause of morbidity and mortality, often complicated by diagnostic uncertainty and antibiotic overuse. This study evaluated the MeMed BV® host-response test in adults with suspected CAP, using clinical management and molecular detection as reference standards. Among 744 patients presenting with suspected CAP at Haukeland University Hospital, Bergen, Norway (2019-2023), across three prospective studies, 453 were included in the present study.
View Article and Find Full Text PDFInt J Infect Dis
September 2025
PandemiX Center of Excellence, Department of Science and Environment, Roskilde University, Denmark.
When a new pandemic virus emerges in a naive population the only control options are Non-Pharmaceutical Interventions, NPI's, until vaccines or effective treatments become available. Here we report on the Danish suppression strategy and use of a combination of NPI's with a notable absence of extremely strict measures (such as stay-at-home orders). Only 7% were infected (serological evidence) in the first year of the pandemic, compared to ∼50% in Lombardy in the first wave alone.
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