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The purpose of this pilot study was to examine the feasibility of a fundamental motor skills (FMS) intervention with two groups on the acquisition of FMS of children with autism spectrum disorders (ASD). We randomly assigned families ( = 15) of children with ASD aged 4-11 years into two groups (a workshop or a home-based group) focused on FMS development. Both groups participated in a 10-week intervention and were given the same instructional manual and adapted physical activity equipment. The workshop group also attended four in-person workshops targeting the needs of children with ASD and their parents. Children were tested on their FMS using the third edition of the Test of Gross Motor Development at the start and end of the intervention and then three months following the intervention. The recruitment rate was 50%, and the retention rate was 80% for all participants. The intervention for groups was safe and accepted by the participants as evaluated by post-program interviews. The outcomes of this pilot study suggest that parents can facilitate the acquisition of FMS of their children with ASD. Although these results are positive, there is a need to further identify effective interventions for FMS development in children with ASD.
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http://dx.doi.org/10.3390/ijerph182312398 | DOI Listing |
Epigenomics
September 2025
College of Physical Education, Yangzhou University, Yangzhou, China.
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder lacking objective biomarkers for early diagnosis. DNA methylation is a promising epigenetic marker, and machine learning offers a data-driven classification approach. However, few studies have examined whole-blood, genome-wide DNA methylation profiles for ASD diagnosis in school-aged children.
View Article and Find Full Text PDFCureus
August 2025
Faculty of Medicine, Universidad de Costa Rica, San José, CRI.
Autism spectrum disorder (ASD) is a neurodevelopmental syndrome that impacts two main areas: social communication and restrictive or repetitive behaviors. Other symptoms and comorbidities may be manifested, according to the different clinical presentations and severity levels. ASD diagnosis can be performed by two years of age; however, certain diagnostic challenges may lead to a late diagnosis and significant intervention delay.
View Article and Find Full Text PDFArch Psychiatr Nurs
October 2025
Ras Al Khaimah Medical and Health Science University, Ras Al Khaimah, United Arab Emirates.
Background & Objectives: The global rise in autism spectrum disorder (ASD) has highlighted the burden on healthcare systems and the significant impact on affected families. This study explored caregivers' perspectives on the healthcare experiences of children with ASD and the related challenges faced by families in Ras Al Khaimah, UAE.
Methods: A descriptive, cross-sectional study was conducted among caregivers of 38 children with confirmed ASD attending two autism centers.
Front Hum Neurosci
August 2025
Signal Processing Laboratory (LTS5), École Polytechnique Féderale de Lausanne (EPFL), Lausanne, Switzerland.
Introduction: Absence of language development is a condition encountered across a large range of neurodevelopmental disorders, including a significant proportion of children with autism spectrum disorder. The neurobiological underpinnings of non-verbal ASD (nvASD) remain poorly understood.
Methods: This study employed multimodal MRI to investigate white matter (WM) microstructural abnormalities in nvASD, focusing on language-related pathways.
Front Child Adolesc Psychiatry
August 2025
Faculty of Medicine, Veracruzana University, Minatitlan, Mexico.
Parents of children with autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) face unique challenges that may significantly increase stress levels, potentially impacting the emotional well-being of the entire family. In Mexico, limited research has examined the association between parental stress and coping strategies among families with children with developmental disabilities. This study aimed to compare stress levels and coping strategies among parents of children with ASD, ADHD, and neurotypical developing (NTD) children, as well as to analyze differences in coping styles across these groups.
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