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We sought to assess the residual effects (post 72-h training cessation) on fasting plasma glucose (FPG) and fasting insulin (FI) after 12-weeks of high-intensity interval training (HIIT), resistance training (RT), or concurrent training (CT) in women with insulin resistance (IR). We also aimed to determine the training-induced, post-training residual impact of CT. A total of adult 45 women (age 38.5±9.2years) were included in the final analysis and were assigned to a control (CG; =13, BMI 28.3±3.6kg/m), HIIT [=14, BMI 28.6±3.6kg/m, three sessions/wk., 80-100% of the maximum heart rate (HR)], RT [=8, BMI 29.4±5.5kg/m, two sessions/wk., 8-10 points of the modified Borg, corresponding to 20 to 50% range of one maximum repetition test (1RM)], or CT group (=10, BMI 29.1±3.0kg/m, three sessions/wk., 80-100% of HR, and 8-10 Borg, or 20 to 50% range of 1RM, to each HIIT and RT compounds), with the latter including both HIIT and RT regimens. Training interventions lasted 12-weeks. The main outcomes were FPG and FI measured at pre- and 24-h and 72-h post-training (FPG, FI, and FPG, FI, respectively). Secondary endpoints were body composition/anthropometry and the adiposity markers waist circumference (WC) and tricípital skinfold (T). The residual effects 72-h post-training [delta (∆)] were significantly poorer (all <0.01) in the CT group (∆FPG+6.6mg/dl, : 0.76) than in the HIIT (∆FPG+1.2mg/dl, : 0.07) and RT (∆FPG+1.0mg/dl, : 0.05) groups. These findings reveal that HIIT reduces FPG and RT reduces FI 24-h post-training; both exercise interventions alone have remarkably better residual effects on FPG and FI (post-72h) than CT in women with insulin resistance.
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http://dx.doi.org/10.3389/fphys.2021.760206 | DOI Listing |
J Speech Lang Hear Res
September 2025
Department of Communication Sciences & Disorders, Montclair State University, Bloomfield, NJ.
Purpose: Residual speech sound disorder (RSSD) is a high-prevalence condition that can limit children's academic and social participation, with negative consequences for overall well-being. Previous studies have described visual biofeedback as a promising option for RSSD, but results have been inconclusive due to study design limitations and small sample sizes.
Method: In a preregistered randomized controlled trial, 108 children aged 9-15 years with RSSD affecting American English /ɹ/ were randomly assigned to receive treatment incorporating visual biofeedback (subdivided into ultrasound and visual-acoustic types) or a comparison condition of motor-based treatment consistent with current best practices in speech therapy.
PLoS One
September 2025
Department of Pathology, Hospital Tuanku Fauziah, Jalan Tun Abdul Razak, Kangar, Perlis, Malaysia.
Cervical cancer remains a significant cause of female mortality worldwide, primarily due to abnormal cell growth in the cervix. This study proposes an automated classification method to enhance detection accuracy and efficiency, addressing contrast and noise issues in traditional diagnostic approaches. The impact of image enhancement on classification performance is evaluated by comparing transfer learning-based Convolutional Neural Network (CNN) models trained on both original and enhanced images.
View Article and Find Full Text PDFMol Pharm
September 2025
Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, U.K.
The presence of water significantly impacts the physical stability of amorphous solid dispersions (ASDs) by altering polymer molecular mobility. This study investigates the influence of low levels of absorbed water on the molecular dynamics and glass transition behavior of amorphous poly(vinylpyrrolidone--vinyl acetate) (PVP/VA). Melt-quenched PVP/VA discs were conditioned at controlled relative humidities (RH 8.
View Article and Find Full Text PDFAm J Prev Cardiol
September 2025
Division of Cardiovascular Medicine, University of California San Diego, La Jolla, CA, USA.
Elevated lipoprotein(a) [Lp(a)] is well established as a common risk factor for atherosclerotic cardiovascular disease (ASCVD). Lp(a) levels are >90 % genetically determined. However, Lp(a) remains very underrecognized as a cardiovascular risk factor with low rates of testing.
View Article and Find Full Text PDFCureus
August 2025
Diagnostic Radiology, Mardan Medical Complex, Mardan, PAK.
Introduction: Fractures are a common occurrence in childhood, with approximately one-third of boys and girls sustaining at least one fracture before the age of 17. Both-bone forearm fractures, particularly those involving the radius and ulna, are more common in the non-dominant hand and in boys and usually involve the distal portions of both bones. If not properly treated, these injuries can have a significant impact on limb function.
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