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Phenethyl isothiocyanate isolated from root oil and its derivatives were tested at different doses in a bioassay designed to evaluate repellency against individual nymphs. Among the tested compounds, benzyl isothiocyanate exhibited repellency against nymphs at the lowest dose of 0.00625 mg/cm, followed by phenethyl isothiocyanate (0.0125 mg/cm) and phenyl isothiocyanate (0.025 mg/cm). The behavioral responses of nymphs exposed to benzyl isothiocyanate and phenethyl isothiocyanate indicated that the mode of action of these compounds can be mainly attributed to the vapor phase. Encapsulated benzyl isothiocyanate showed repellency up to 120 min post-application at 0.1 mg/cm, whereas pure benzyl isothiocyanate showed repellency up to 60 min post-application at 0.1 mg/cm. The present study suggests that benzyl isothiocyanate is a potential repellent for protection against nymphs, and encapsulation in yeast cells may enhance the repellency effect.
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http://dx.doi.org/10.3390/molecules26226817 | DOI Listing |
Pestic Biochem Physiol
November 2025
Key Laboratory of Plant Protection Resources and Pest Management of Ministry of Education, College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi, China; Key Laboratory of Integrated Pest Management on Crops in Northwestern Loess Plateau of Ministry of Agriculture and Rural
The olfactory system of insects plays a vital role in their survival by enabling them to detect chemical cues and adapt to changing environments. The rape stem weevil, Ceutorhynchus asper, is a significant pest posing a challenge for rapeseed production due to its destructive feeding habit and increasing resistance to insecticides. So far, there's still limited knowledge about structure and function of odorant binding proteins (OBPs) in beetles like C.
View Article and Find Full Text PDFInt J Mol Sci
July 2025
Yunnan Key Laboratory of Modern Separation Analysis and Substance Transformation, College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, China.
In this study, using 70% anhydrous ethanol as the extraction solvent, Lam. seed powder was extracted with the microwave-assisted extraction method, followed by purification using macroporous adsorbent resin NKA-9. The purified glucosinolate was subsequently hydrolyzed with myrosinase.
View Article and Find Full Text PDF3 Biotech
September 2025
Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, 20130 Kuala Terengganu, Terengganu Malaysia.
Unlabelled: This study investigated the synergistic cytotoxic effects of benzyl isothiocyanate (BITC) and caffeic acid (CA) on human breast adenocarcinoma (MCF-7) cells. Cell viability assays (MTT) revealed that BITC induces reactive oxygen species (ROS)-mediated cell death, while CA alone exhibited minimal cytotoxicity. Notably, their combination selectively enhanced MCF-7 cell death with limited effects on human fibroblasts.
View Article and Find Full Text PDFDrug Deliv
December 2025
School of Pharmacy, Hainan Medical University (Hainan Academy of Medical Sciences), Haikou, China.
is the most prominent conditional fungal pathogen, which can cause systemic candidiasis when an individual becomes immunocompromised. The widespread and long-term use of azoles like fluconazole (FLC) has led to a significant increase in drug resistance, posing substantial challenges to clinical treatment. In our previous study, benzyl isothiocyanate (BITC) was extracted from L.
View Article and Find Full Text PDFLife (Basel)
June 2025
CQM-Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9020-105 Funchal, Portugal.
The garden Nasturtium ( L.) is increasingly consumed worldwide due to its culinary appeal and perceived health benefits. However, the chemical markers underlying its functional properties remain insufficiently characterized.
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