Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: One of the treatment goals in type 1 diabetes and periodontitis is to address chronic inflammation to prevent the development of neurovascular complications. The aim of this study was to assess the local anti-inflammatory effects of chlorhexidine digluconate and cetylpyridine chloride on periodontal status and indicators of oxidative stress in saliva in patients with type 1 diabetes.
Materials And Methods: A total of 42 subjects aged 27 (interquartile range, IQR 22-35) years, with type 1 diabetes for a duration of 12 (IQR 9-18) years, and glycated hemoglobin 8.05 (IQR 7.1-9.4)% were included. Patients were examined twice-initially, and after 14 days of using toothpaste with chlorhexidine and cetylpyridine. Clinical examination of gingival tissues was performed. Certain oxidative stress markers (TP, TEAC, TBARS, AOPP) were measured in the saliva samples.
Results: There were significant changes in clinical indicators of periodontal status before and after the application of the toothpaste (API before 0.35 (0.24-0.65) vs. API after 0.265 (0.18-0.39), = 0.03; SBI before 0.07 (0.04-0.15) vs. SBI after 0.035 (0-0.06), = 0.002; GI before 0.88 (0.46-1) vs. GI after 0.67 (0.25-1), = 0.0008). The concentration of saliva TBARS decreased ( = 0.00005) and TEAC increased ( = 0.09).
Conclusion: Proper oral hygiene supported by antibacterial chemicals may improve the periodontal status and reduce inflammation.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614958 | PMC |
| http://dx.doi.org/10.3390/antiox10111732 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effect of dentition status on perceived mobility limitation among older Brazilian adults: a cohort study.
Braz Oral Res
September 2025
Universidade de São Paulo - USP, School of Medicine of Ribeirão Preto, Ribeirão Preto, SP, Brazil.
This study aimed to evaluate the longitudinal effect of dentition status on the perceived mobility limitation of community-dwelling Brazilian older adults. This cohort study used data from individuals who participated in the second (2006), third (2010), and fourth (2015) waves of the Health Well-being and Aging Study, conducted in the urban region of the city of São Paulo, Brazil, with adults aged 60 years and older. Mobility limitation was assessed in all waves according to reports of difficulty in performing seven activities, with higher scores representing a higher number of limitations.
View Article and Find Full Text PDFAssociation Between Oral Health and Physical Frailty in an Adult Community-Dwelling Caucasian Population.
J Oral Rehabil
September 2025
Department of Prosthodontics, Dental School, National and Kapodistrian University of Athens, Athens, Greece.
Background: Although oral diseases and frailty can be met earlier in life, there is limited information on their association across the lifespan.
Objectives: To scope for the association of oral factors with physical frailty in Greek community-dwelling adults.
Methods: Participants were over 18 years of age with ≥ 20 natural teeth, ≥ 10 occlusal contacts, and no removable dentures.
Fibre or facade? Do fibre reinforced composites really hold up in Class II restorations?
Evid Based Dent
September 2025
Dental Core Trainee, Restorative Dentistry, Newcastle Dental Hospital, Cairo, Egypt.
A Commentary On: Mohamed M H, Abouauf E A, Mosallam R S. Clinical performance of class II MOD fiber reinforced resin composite restorations: an 18-month randomized controlled clinical trial. BMC Oral Health 2025;25: 159.
View Article and Find Full Text PDFApolipoprotein E4 allele, antibodies against periodontal microorganisms, and cognition in older adults.
J Alzheimers Dis Rep
September 2025
Communication Sciences and Disorders, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Background: The presence of the apolipoprotein E4 () allele and periodontal disease are independently correlated with higher levels of amyloid-β and inflammation in the brain, worse cognition, and Alzheimer's disease.
Objective: To assess whether the presence of the allele modifies the relationship between IgG antibodies against periodontal microorganisms and cognitive function in older adults participating in the NHANES III study.
Methods: This cross-sectional analysis was conducted among participants of the third National Health and Nutrition Examination Survey (NHANES III) (1988 to 1994), aged 60 years and older, with measurements of IgG antibodies against 19 periodontal microorganisms and alleles (N = 1644).
Associations Between Maternal Emotional States and Plaque Accumulation in Three-Year-Old Children: A Proxy Indicator of Caregiving Quality.
Cureus
August 2025
Department of Children and Women's Health, The University of Osaka Graduate School of Medicine, Osaka, JPN.
Background Plaque accumulation can lead to dental caries and periodontal disease and may reflect overall oral health status. As mothers are often the primary caregivers for children's oral hygiene, plaque in children may also serve as a proxy for caregiving quality. This study examined whether maternal emotional states are associated with the quality of caregiving, using children's plaque accumulation as a proxy indicator.
View Article and Find Full Text PDF