Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Fat/carbohydrate-rich diet consumption or elevated secretion of pancreatic lipase (PL) in pancreatic injury results in increased fat digestion and storage. Several metabolites in plant-based diets can help achieve the requirements of nutrition and fitness together. Presently, nutritional metabolites from , , and were assessed and predicted for daily intake. The volatile-metabolite profiling of their extracts using GC-MS revealed various antioxidant and bioactive components. The implication of these specialized components and antioxidant-rich extracts (EC free radical scavenging: 34.1 ± 1.5 to 166.3 ± 14.2 µg/mL; FRAP values: 12.1 ± 1.0 to 34.0 ± 2.0 µg Trolox Equivalent/mg) in lipolysis regulation by means of interaction with PL was checked by in silico docking (Betahistine and vitamins: ΔGbind -2.3 to -4.4 kcal/mol) and in vitro fluorescence quenching. Out of the various compounds and extracts tested, Betahistine, ATRA and AVLA showed better quenching the PL fluorescence. The identification of potential extracts as source of functional components contributing to nutrition and fat regulation can be improved through such study.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8539516 | PMC |
| http://dx.doi.org/10.3390/metabo11100676 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effects of Pomegranate on Wound Healing.
Cureus
July 2025
General Surgery, Faculty of Health Sciences, Istanbul Esenyurt University, Istanbul, TUR.
Background: Sepsis disrupts normal wound healing and causes organ damage through a systemic inflammatory response. Pomegranate () is a natural antioxidant rich in polyphenols, such as ellagitannins and punicalagins, and has demonstrated potential anti-inflammatory and tissue-healing properties in various preclinical models.
Objective: This study aimed to evaluate the effects of pomegranate extract administered before and after sepsis induction on wound healing in a cecal ligation and puncture (CLP) rat model.
Nanostructured Lipid Carriers for Sustained Release and Enhanced Delivery of Protocorm Extract.
Pharmaceutics
August 2025
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
This study aimed to develop a nanostructured lipid carrier (NLC) system incorporating a catechin-rich extract for topical cosmetic applications and to evaluate its physicochemical properties, release behavior, and skin retention performance. Blank NLCs were prepared using hot emulsification followed by sonication, with glyceryl monostearate, caprylic triglyceride, Poloxamer 188, and Tween 80 as the formulation components. NLCs with varying solid-to-liquid lipid ratios were developed while maintaining a constant total lipid content of 5% /.
View Article and Find Full Text PDFTherapeutic Potentials of Jamun () and Its Integration Into Modern Food Technologies: A Review.
Int J Food Sci
August 2025
Department of Food Technology and Nutrition, School of Agriculture, Lovely Professional University, Phagwara, Punjab, India.
In a world where consumer preferences continue to pivot toward healthier and eco-conscious choices, jamun () emerges as an underutilized resource with untapped potential. Despite the abundance of phytochemicals, the fruit also encounters postharvest losses, pointing toward extensive processing and additional research for sustainable utilization of food. The review brings together an understanding of existing knowledge on the therapeutic potentials of jamun and its integration into modern food technologies, providing valuable insights for food researchers and healthcare professionals aiming to leverage the health-promoting properties of this remarkable fruit to enhance human well-being.
View Article and Find Full Text PDFComparative efficiency of extraction techniques for bioactive compounds in Cinnamomum zeylanicum.
Food Chem
August 2025
Riddet Institute, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Electronic address:
Cinnamomum zeylanicum is a plant well-known for its antioxidant-rich bioactives. This study assessed its total phenolic (TPC) and flavonoid contents (TFC), antioxidant activity, and key bioactives (cinnamaldehyde, eugenol, and cinnamic acid) using two extraction methods: accelerated solvent extraction (ASE) and ultrasonic-assisted extraction (UAE), with solvents including ethanol, methanol, acetone, and water. ASE with 50 % ethanol yielded the highest TPC (6.
View Article and Find Full Text PDFPotential of Plant-Based Oil Processing Wastes/By-Products as an Alternative Source of Bioactive Compounds in the Food Industry.
Foods
August 2025
Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical University, 34469 Maslak, Istanbul, Turkey.
The plant-based oil industry contributes significantly to food waste/by-products in the form of underutilized biomass, including oil pomace, cake/meal, seeds, peels, wastewater, etc. These waste/by-products contain a significant quantity of nutritious and bioactive compounds (phenolics, lignans, flavonoids, dietary fiber, proteins, and essential minerals) with proven health-promoting effects. The utilization of them as natural, cost-effective, and food-grade functional ingredients in novel food formulations holds considerable potential.
View Article and Find Full Text PDF