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http://dx.doi.org/10.1016/j.xjtc.2021.07.001 | DOI Listing |
Res Social Adm Pharm
November 2025
School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Pharmacy and Bank Building A15, Science Rd, New South Wales, 2006, Australia. Electronic address:
Large language models (LLMs), such as ChatGPT (OpenAI), represent a paradigm shift in the application of artificial intelligence (AI) across various fields, including healthcare. In pharmacy research, LLMs have demonstrated potential utility, though challenges regarding response reproducibility, inconsistent accuracy, and information privacy persist. While LLMs can generate functional code, the usefulness of this capability for pharmacists remains underexplored.
View Article and Find Full Text PDFImportance: Untreated syphilis infection during pregnancy can be passed to the fetus, causing congenital syphilis. Congenital syphilis is associated with premature birth, low birth weight, stillbirth, neonatal death, and significant abnormalities in the infant such as deformed bones, anemia, enlarged liver and spleen, jaundice, brain and nerve problems (eg, permanent vision or hearing loss), and meningitis. In 2023, there were 3882 cases of congenital syphilis in the US, including 279 congenital syphilis-related stillbirths and neonatal/infant deaths, the highest number reported in more than 30 years.
View Article and Find Full Text PDFJAMA Ophthalmol
June 2025
Eye Clinic, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Importance: Recently, it was proved that the large language model Generative Pre-trained Transformer 4 (GPT-4; OpenAI) can fabricate synthetic medical datasets designed to support false scientific evidence.
Objective: To uncover statistical patterns that may suggest fabrication in datasets produced by large language models and to improve these synthetic datasets by attempting to remove detectable marks of nonauthenticity, investigating the limits of generative artificial intelligence.
Design, Setting, And Participants: In this quality improvement study, synthetic datasets were produced for 3 fictional clinical studies designed to compare the outcomes of 2 alternative treatments for specific ocular diseases.
Med Sci Educ
February 2025
Department of Medicine, University of Massachusetts TH Chan School of Medicine, Worcester, MA USA.
The USMLE Step 1 exam provides a standardized metric by which medical schools and residency programs can assess a medical student's preclinical medical education. In 2021, the grading of Step 1 changed to pass/fail, in an effort to improve student wellbeing and reduce the exam's undue influence on the residency match process. This commentary provides a medical student's perspective on the new grading system, highlighting recent studies on Step 1 student wellbeing, financial stress, and residency influence.
View Article and Find Full Text PDFCurr Pharm Teach Learn
June 2025
UW School of Pharmacy Box 357630, 1959 NE Pacific Street, University of Washington, Seattle, WA 98195, United States. Electronic address:
Not passing the North American Pharmacy Licensure Examination (NAPLEX) is the reality for a significant number of PharmD graduates. The average first time pass rates for the NAPLEX have experienced significant drops since 2017, hitting an all-time low (76.6 %) for the Class of 2023.
View Article and Find Full Text PDF