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http://dx.doi.org/10.1016/S2468-1253(21)00336-8 | DOI Listing |
BJGP Open
September 2025
School of Medicine, University of St Andrews, St Andrews, Scotland, United Kingdom.
Background: People living with and dying from multiple long-term health conditions are high users of healthcare services. Unscheduled care, the unplanned use of healthcare services, rises dramatically in the last year of life, likely reflecting unmet needs.
Aim: To characterise Scotland-based decedents with multiple long-term health conditions in their last year of life and explore the relationship between characteristics and unscheduled care usage over that year.
Int J Pharm
September 2025
Department of Biomedical Engineering, Amirkabir University of Technology (Tehran polytechnic), Iran. Electronic address:
Hydrogen sulfide (HS) has been recognized as one of the three main gasotransmitters found extensively in tissues, regulating functions crucial for survival. In many pathological cases, its concentration drops from the intrinsic level, impairing healing and leading to unmet regeneration outcomes. A hybrid microparticle/hydrogel system was developed to sustainably release HS and regulate its level in deprived tissues.
View Article and Find Full Text PDFHealth Expect
October 2025
School of Pharmacy, Newcastle University, Newcastle Upon Tyne, UK.
Introduction: There remains limited research exploring the experiences of informal carers from ethnically minoritised groups, particularly to illustrate perceptions of caring roles and challenges they may face to address unmet needs. While barriers such as language, cultural expectations and discrimination are acknowledged in wider literature, little is known about how these influence caregiving experiences or access to services in practice. This work seeks to better describe the barriers and facilitators impacting carers from ethnically minoritised groups, as well as illustrate possible influences of culture and carer identity affecting this under-researched population.
View Article and Find Full Text PDFA A Pract
September 2025
Department of Anesthesiology, Ospedale San Giovanni, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Childbirth-Related Posttraumatic Stress Disorder (CB-PTSD) can arise even after low-risk deliveries. This case report describes a 35-year-old woman who, despite a medically uncomplicated vaginal birth, developed severe CB-PTSD after being denied neuraxial analgesia and receiving remifentanil-PCA (remi-PCA) to manage pain. Her distress stemmed from inadequate pain relief, dissociation, and loss of control, exacerbated by unmet expectations for epidural analgesia.
View Article and Find Full Text PDFCancer Med
September 2025
Department of Pulmonary Medicine, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Background: The prognosis of small-cell lung cancer (SCLC) remains poor, particularly in patients with extensive-stage SCLC. The IMpower133 and CASPIAN trials revealed the efficacy of immune checkpoint inhibitors (ICIs) in extensive-stage SCLC patients with good performance status (PS). The aim of this study was to investigate the efficacy of ICIs in patients with poor PS.
View Article and Find Full Text PDF