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Permanent His bundle pacing is a physiological alternative to right ventricular pacing, resulting in a lower probability of pacing-induced cardiomyopathy and left ventricular ejection fraction deterioration. The combined use of UHD mapping systems allows precise and detailed information on the His bundle location, possibly providing more pacing option locations.
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http://dx.doi.org/10.1002/ccr3.4477 | DOI Listing |
J Neurosci
September 2025
Centre for Functional and Metabolic Mapping, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada.
Vocal communication is a complex social behavior that entails the integration of auditory perception and vocal production. Both anatomical and functional evidence have implicated the anterior cingulate cortex (ACC), including area 32, in these processes, but the dynamics of neural responses in area 32 during naturalistic vocal interactions remain poorly understood. Here, we addressed this by recording the activity of single area 32 neurons using chronically implanted ultra high density Neuropixels probes in freely moving male common marmosets () engaged in an antiphonal calling paradigm in which they exchanged long-distance "phee" calls with a virtual conspecific.
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August 2025
Department of Electronics, Graduate School of Engineering, Tohoku Institute of Technology, Sendai, Japan.
Introduction: Human iPSC-derived brain organoids and assembloids have emerged as promising in vitro models for recapitulating human brain development, neurological disorders, and drug responses. However, detailed analysis of their electrophysiological properties requires advanced measurement techniques.
Methods: Here, we present an analytical approach using ultra-high-density (UHD) CMOS microelectrode arrays (MEAs) with 236,880 electrodes across a 32.
Biomedicines
August 2025
Cardiology and Cardiac Surgery Department, Clínica Universidad de Navarra, Avenida Pio XII 36, 31008 Pamplona, Spain.
: Atrial fibrosis is a key contributor to atrial cardiomyopathy and can be assessed invasively using mean left atrial voltage (MLAV) from electroanatomical mapping. However, the invasive nature of this procedure limits its clinical applicability. Machine learning (ML), particularly regression tree-based models, may offer a non-invasive approach for predicting MLAV using clinical and echocardiographic data, improving non-invasive atrial fibrosis characterisation beyond current dichotomous classifications.
View Article and Find Full Text PDFCirc Arrhythm Electrophysiol
August 2025
Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Servicio de Cardiología, Hospital General Universitario Gregorio Marañón, Madrid, Spain (A.C.-B., J.B., A.A.-M.).
Background: Identification of fast ventricular tachycardia (FVT; cycle length <320 ms) isthmuses is often hindered by hemodynamic instability during sustained FVT and by rate-dependent (functional) scar properties. Comparing ultra-high-density voltage heterogeneity maps (0.1-1.
View Article and Find Full Text PDFHortic Res
July 2025
National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crop, The Key Laboratory of Biology and Genetic Improvement of Horticultural Crops (Fruit Tree Breeding Technology), Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Ministry of Agriculture a
Increasing marker density results in better map coverage and efficiency of genetic analysis. Here, we resequenced a large ( = 235) F1 progeny from two distant peach cultivars, 'Zhongyou Pan #9' and 'September Free', and constructed two parental maps (1:1 segregations) and one combined map (1:2:1 segregations) with 134 277 SNPs. Markers with the same genotype for all individuals studied were grouped in bins and a unique genotype for each bin was inferred to avoid mapping problems derived from erroneous data.
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