Post-SARS-CoV-2 vaccination specific antibody decrease - Thresholds for determining seroprevalence and seroneutralization differ.

J Infect

University of Namur, Department of Pharmacy, Namur Research Institute for Life Sciences, Rue de Bruxelles, 61, Namur 5000, Belgium; Clinique Saint-Luc Bouge, Department of Laboratory Medicine, Namur, Belgium.

Published: October 2021


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8364678PMC
http://dx.doi.org/10.1016/j.jinf.2021.08.023DOI Listing

Publication Analysis

Top Keywords

post-sars-cov-2 vaccination
4
vaccination specific
4
specific antibody
4
antibody decrease
4
decrease thresholds
4
thresholds determining
4
determining seroprevalence
4
seroprevalence seroneutralization
4
seroneutralization differ
4
post-sars-cov-2
1

Similar Publications

The COVID-19 pandemic significantly impacted the circulation, seasonality, and disease burden of viral respiratory infections. This study aimed to evaluate the impact of SARS-CoV-2 on the frequency of viral respiratory infections at a teaching hospital in Southern Italy by comparing data from before, during, and after the COVID-19 pandemic and by investigating how the emergence of SARS-CoV-2 affected the circulation and seasonality of other respiratory viruses. This retrospective and prospective study was performed on de-identified nasopharyngeal specimens classified as pre-COVID-19 (before 15 March 2020), during-COVID-19 (from 16 March 2020 to 5 May 2023), and post-COVID-19 (from 6 May 2023 to 31 December 2024).

View Article and Find Full Text PDF

SARS-CoV-2 spike antibody and T cell response in MS patients on high efficacy therapies post vaccine.

J Neuroimmunol

October 2025

Brigham Multiple Sclerosis Center, Department of Neurology, Brigham and Women's Hospital, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

Background: There is limited knowledge about SARS-CoV-2 spike antibody and long-term T cell responses in multiple sclerosis (MS) patients on high efficacy treatments post SARS-CoV-2 vaccine.

Objectives: To assess spike antibody and T cell responses in MS patients on fingolimod (FIN), ocrelizumab (OCR) and healthy controls (HC) post vaccine.

Methods: We studied spike antibody seroconversion rates and T cell responses by flow cytometry in HC and MS patients.

View Article and Find Full Text PDF

Background: Fatigue is a common sequela of SARS-CoV-2 infection, with many COVID-19 patients subsequently developing chronic fatigue syndrome and myalgic encephalomyelitis (CFS/ME). Long-term associations between COVID-19, new-onset CFS/ME, and other independent predictors such as vaccination for SARS-CoV-2, re-infection, and blood biomarkers at time of infection remain unclear. This study investigated the incidence and independent predictors of developing new-onset CFS/ME up to 4 years post SARS-CoV-2 infection in comparison to COVID- controls.

View Article and Find Full Text PDF

COVID-19 vaccines proved vital in controlling the SARS-CoV-2 pandemic. Both neutralizing and effector-function activities of Spike-specific antibodies are important for their protective activity. Several studies have reported that COVID-19 mRNA vaccines can lead to elevated levels of Spike-specific immunoglobulin G4 (IgG4), an anti-inflammatory subclass with reduced binding to Fcγ receptors.

View Article and Find Full Text PDF

Lack of Treatment Efficacy and Duration of OnabotulinumtoxinA and AbobotulinumtoxinA Post Sars-COV-2 Infection and COVID Vaccination.

Plast Aesthet Nurs (Phila)

July 2025

Ali McCoy Stengel, BSN, RN, LE, is the founder/owner of Always Beautiful Medspa, Institute, and CoolClinic, in Aurora, CO. Ali is a national Allergan trainer who has administered 700,000 Botox units and is ranked Top 5 in Botox retention.

This article outlines the data collection process we used to document treatment efficacy and longevity changes in 1,298 patients who received a total of 4,583 treatments with either onabotulinumtoxinA, abobotulinumtoxinA, or both during the Sars-COV-2 (COVID-19) pandemic outbreak in 2020 and the adult COVID-19 vaccination program rollout in 2021. We divided the study patients into two groups based on the year they were treated (2020 = 791; 2021 = 1,037). We did not include any new patients in the study.

View Article and Find Full Text PDF