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Congenital rubella syndrome (CRS) results from maternal rubella virus infection in early pregnancy. Abnormal neuroimaging findings have been analyzed in a small number of CRS patients in the past; however, their clinical significance has been poorly addressed. Therefore, we have investigated the neuroimaging findings of 31 patients with CRS from previous studies. The most common finding was parenchymal calcification, which was observed in 18 of 31 patients (58.1%). A multivariable logistic regression model showed that it was associated with psychomotor or mental retardation (p = 0.018), suggesting that parenchymal calcification in CRS could be a prognostic factor.
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http://dx.doi.org/10.1111/cga.12442 | DOI Listing |
Radiol Case Rep
October 2025
Department of radiology, college of health science, Addis Ababa University, Addis Ababa, Ethiopia.
Intracranial calcification in pediatric patients below the age of 6 years is almost always pathologic. There are several causes of intracranial calcification, including congenital intracranial arteriovenous malformations, congenital infections, and neoplasms. Vein of Galen aneurysmal malformation is the most common of the congenital intracranial arteriovenous malformations.
View Article and Find Full Text PDFTurk J Surg
September 2025
Department of Surgical Gastroenterology, All India Institute of Medical Sciences, Patna, India.
Objective: Chronic pancreatitis (CP) leads to enduring abdominal pain and functional insufficiency, alongside notable risks posed by vascular complications. Pseudoaneurysms (PSA) are common in CP, necessitate careful management due to potential life-threatening hemorrhage. Literature suggests a 5-10% incidence of gastrointestinal bleeding in CP, often related to PSA affecting nearby arteries.
View Article and Find Full Text PDFTomography
June 2025
Department of Radiology, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
Background/objectives: Spread through air spaces (STAS) is defined as the spread of tumor cells into the parenchymal alveolar space beyond the margins of the main tumor, and it is associated with worse clinical outcomes in resected lung adenocarcinoma. This study aimed to evaluate the preoperative computed tomography (CT) findings of primary lung adenocarcinoma in surgically resected T1 cases and to compare CT findings with and without STAS.
Methods: A total of 145 patients were included in this study.
Can Respir J
July 2025
Department of Cardiology, Royal Papworth Hospital, Cambridge, UK.
Systemic sclerosis (SSc) is predominantly characterized by an array of cutaneous manifestations including Raynaud's phenomenon, calcinosis, telangiectasias, and skin fibrosis contributing toward substantial morbidity and diminished quality of life. The monumental impact of the disease regarding mortality is due to its pulmonary involvement known as SSc-associated interstitial lung disease (SSc-ILD). Currently, treatment is chiefly directed toward impeding disease progression with the mainstay treatment approaches involving the utilization of cyclophosphamide, mycophenolate mofetil, rituximab, and tocilizumab.
View Article and Find Full Text PDFRheumatol Adv Pract
May 2025
Department of Clinical Immunology and Rheumatology, Institute of Postgraduate Medical Education and Research (IPGMER), Kolkata, India.
Objectives: Monogenic systemic lupus erythematosus (SLE) is caused by a single gene mutation. C1q deficiency is a rare but well-documented form of monogenic SLE, characterized by unique clinical and laboratory indicators that guide diagnosis and treatment. We aimed to describe four cases of C1q monogenic lupus.
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