Phosphate binders in dialysis: better satisfied than sorry.

Clin Kidney J

Renal Research Laboratory, Department of Nephrology, Dialysis and Renal Transplant, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Published: August 2021


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

High serum phosphate levels have been associated with increased morbidity and mortality in dialysis patients. Nephrologists routinely counteract the positive phosphate balance in dialysis patients through nutritional counselling, stronger phosphate removal by dialysis and prescription of phosphate binders. An individualized choice of phosphate binders is a desirable option to improve the poor adherence with these medications' prescription that has been associated with hyperphosphataemia.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323148PMC
http://dx.doi.org/10.1093/ckj/sfab093DOI Listing

Publication Analysis

Top Keywords

phosphate binders
12
dialysis patients
8
phosphate
6
dialysis
4
binders dialysis
4
dialysis better
4
better satisfied
4
satisfied high
4
high serum
4
serum phosphate
4

Similar Publications

Introduction: Information on tertiary hyperparathyroidism (THPTH) among chronic kidney disease (CKD) patients on haemodialysis in developing countries such as India is limited, and the mortality among them remains a query.

Materials And Methods: This was a prospective cohort study conducted in at a tertiary care centre from June 2017 to June 2022. The index of suspicion for tertiary hyperparathyroidism was when investigations revealed high serum calcium and high alkaline phosphatase along with new onset of body aches, joint pains, and difficulty in walking.

View Article and Find Full Text PDF

Bioactive hydroxyapatite-sodium silicate waterglass reinforced with nanocollagen from Chitala ornata fish skin for bone engineering.

Int J Biol Macromol

September 2025

The Materials Engineering Department, Faculty of Engineering, Kasetsart University, Phaholyothin Rd., Bangkok 10900, Thailand. Electronic address:

A prototype bioactive calcium phosphate model-specifically hydroxyapatite (HA) derived from eggshells-was developed using a sodium silicate (NaSiO) solution as an inorganic binder, precursor, and reinforcing agent, in combination with collagen nanofibers for bone engineering applications. The sodium silicate solution, functioning as a waterglass adhesive, introduced cohesive forces within the hydroxyapatite matrix, thereby enhancing its physical, chemical, and mechanical properties. Eggshell-derived bioactive hydroxyapatite offers several advantages, including non-toxicity, biocompatibility, collagen adhesion, and the ability to mimic bone structure, making it suitable for tissue engineering.

View Article and Find Full Text PDF

Vascular calcification is common in dialysis patients and is severely associated with cardiovascular morbidity and mortality. They have mineral metabolism disorders, which are considered to promote vascular calcification. In addition, hypertension and malnutrition, both prevalent in dialysis patients, are also considered risk factors contributing to vascular calcification.

View Article and Find Full Text PDF

Sodium-ion batteries (SIBs) are considered the most promising candidate for electrochemical storage after lithium-ion batteries (LIBs) to meet the globally growing energy storage demand. Assessments to identify environmental hotspots and address them in further development at regular intervals are inevitable to ensure low environmental impact of SIBs in the future. However, the number of studies assessing the environmental impacts of SIBs is limited, and existing studies are mostly based on theoretical models and few limited sources.

View Article and Find Full Text PDF