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Scrofuloderma is one of the cutaneous manifestations of tuberculosis and usually occurs when underlying tuberculosis such as lymphadenitis directly involves the skin. However, the diagnosis of scrofuloderma without other apparent clinical manifestations of tuberculosis is sometimes challenging. A 27-year-old male from Bangladesh presented with a dome-shaped tumor on his right clavicle. MRI showed a high-density area that expanded from the lymph nodes between the internal jugular vein and the common carotid artery into the tumor on his right clavicle. Bacterial examinations of cultures from the tumor detected . Further examinations for pulmonary tuberculosis including chest X-ray and computed tomography did not detect any lesions suggestive of pulmonary tuberculosis. From those examinations, the diagnosis of scrofuloderma was made. We emphasize the importance of recognizing a variety of clinical manifestations of tuberculosis including scrofuloderma due to the recent increase of immigrants from developing countries.
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http://dx.doi.org/10.1159/000515983 | DOI Listing |
Background: Actinomyces graevenitzii is a relatively uncommon Actinomyces species, which is an oral species and predominantly recovered from respiratory locations [1,2]. It is a gram-positive anaerobic bacteria or microaerobic filamentation bacteria, which can induce pyogenic and granulomatous inflammation characterized by swelling and concomitant pus, sinus formation, and the formation of yellow sulfur granules. All tissues and organs can be infected; the most common type involves the neck and face (55%), followed by the abdominal and pelvic cavities (20%).
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August 2025
General Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Ankylosing spondylitis (AS) is a chronic inflammatory spondyloarthropathy that predominantly affects the axial skeleton. While hallmark features such as sacroiliitis and syndesmophytes are well recognized, the presence of mediastinal masses may pose a diagnostic dilemma and raise concerns for malignancy or atypical infection. We report a middle-aged man in the fifth decade of life with longstanding untreated AS presenting with progressive quadriparesis.
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August 2025
Pulmonology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Common variable immunodeficiency (CVID) is a rare immunodeficiency syndrome presenting with wide manifestations and leading to a delayed diagnosis. A 40-year-old male, a case of old treated tuberculosis, presented with a productive cough and hemoptysis. He had a history of recurrent respiratory symptoms previously attributed to post-tuberculosis sequelae with bilateral bronchiectasis, which can also occur as a manifestation of underlying common variable immunodeficiency (CVID).
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August 2025
Department of Infectious Diseases, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Aims: In this study, we aimed to analyze the pathogen detection results in spinal infections using percutaneous CT-guided biopsy or transforaminal endoscopic spinal biopsy.
Methods: This is a retrospective observational study of patients who underwent biopsy for spinal infection at Shanghai Sixth People's Hospital between December 2020 and June 2024. Data on demographics, clinical presentations, radiological findings, and histopathology were collected from medical records.
Cureus
August 2025
Neurology, Government Medical College, Amritsar, Amritsar, IND.
Tubercular (TB) meningitis is one of the manifestations of central nervous system tuberculosis, a form of extrapulmonary tuberculosis. Despite the high incidence of TB meningitis in developing countries, there are hardly any reports of associated ventriculitis, making it one of the rare complications. Ventriculitis complicating TB meningitis is devastating not only to the immunocompromised but also to the immunocompetent population.
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