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http://dx.doi.org/10.23736/S2724-5985.21.02970-3 | DOI Listing |
Cureus
August 2025
Biochemistry, Liaquat University of Medical and Health Sciences, Karachi, PAK.
Background: Vitamin D insufficiency is increasingly recognized as a significant and underlying contributor to a wide range of musculoskeletal disorders, particularly in gastrointestinal (GI) and endocrine health. The study aims to determine the clinical relationship between vitamin D status and the severity of GI symptoms, while also assessing the impact of related endocrine disturbances.
Methods: A cross-sectional study was conducted involving 120 adult patients with GI problems, including constipation, bloating, irritable bowel syndrome (IBS), and dyspepsia in a tertiary care hospital over a six-month duration.
J Ayurveda Integr Med
September 2025
Department of Gastroenterology, Lala Lajpat Rai Memorial Medical College, Meerut, India.
Background: The most common cause of acid-peptic diseases (APDs) is Helicobacter Pylori (H. pylori) infection. Conventionally, proton-pump inhibitors (PPIs) are used to manage hyperacidity and dyspepsia.
View Article and Find Full Text PDFPediatr Nephrol
September 2025
Pediatric Urology Unit, "Santobono-Pausilipon" Children's Hospital, Naples, Italy.
Voiding cystourethrography (VCUG) is indicated for evaluating the anatomy of the urethra and bladder. It is primarily used to diagnose vesicoureteral reflux (VUR) and posterior urethral valves (PUV), especially in cases of febrile urinary tract infections (UTIs), significant ureteral dilation on ultrasound, and-in continent children-urinary symptoms suggestive of infravesical obstruction. VCUG exposes children to a non-negligible dose of radiation and requires urethral catheterization, which can be painful-particularly in males-and carries a low but present risk of post-procedural UTI.
View Article and Find Full Text PDFCurr Opin Gastroenterol
July 2025
Division of Gastroenterology, Washington University School of Medicine, St. Louis, Missouri, USA.
Purpose Of Review: Acid suppression is the mainstay of management of common foregut disorders, including gastroesophageal reflux disease (GERD), peptic ulcer disease and Helicobacter pylori infection. Drawbacks of standard management with proton pump inhibitors (PPIs) include acid lability requiring enteric coating, slow onset of effect, lack of suppression of nocturnal acid breakthrough, and need for administration before meals.
Recent Findings: Potassium-competitive acid blockers (PCABs) are a novel class of acid suppressants that are effective in the management of symptomatic and erosive GERD, peptic ulcer disease and H.
Medicine (Baltimore)
September 2025
School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, China.
Gastroesophageal reflux disease (GERD) is linked to various esophageal and extra-esophageal complications. While GERD is theoretically a potential risk factor for abdominal hernias, current evidence is limited. Observational studies have suggested associations between GERD and both congenital diaphragmatic hernia and hiatal hernia.
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