Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
We provide a proof of principle for an evolutionary systems theory (EST) of depression. This theory suggests that normative depressive symptoms counter socioenvironmental volatility by increasing interpersonal support via social signalling and that this response depends upon the encoding of uncertainty about social contingencies, which can be targeted by neuromodulatory antidepressants. We simulated agents that committed to a series of decisions in a social two-arm bandit task before and after social adversity, which precipitated depressive symptoms. Responses to social adversity were modelled under various combinations of social support and pharmacotherapy. The normative depressive phenotype responded positively to social support and simulated treatments with antidepressants. Attracting social support and administering antidepressants also alleviated anhedonia and social withdrawal, speaking to improvements in interpersonal relationships. These results support the EST of depression by demonstrating that following adversity, normative depressed mood preserved social inclusion with appropriate interpersonal support or pharmacotherapy.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610949 | PMC |
| http://dx.doi.org/10.5334/cpsy.70 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
In-Flight Deterioration Occurs Early in Aeromedical Trauma Patients.
Emerg Med Australas
October 2025
Australian Centre for Health Services Innovation, School of Public Health & Social Work, Queensland University of Technology, Brisbane, Queensland, Australia.
Reliably defining the risk of adverse in-flight events in aeromedical trauma patients could enable more informed pre-departure treatment and guide central asset allocation to achieve better system-level outcomes. Unfortunately, the current literature base specifically examining the in-flight period is sparse. Flight duration is often considered a proxy for the risk of in-flight deterioration; however, there is limited data to support this commonly held assumption.
View Article and Find Full Text PDFResearch on statistical measure under double carbon target - Self-moving regression model of grey prediction based on entropy weight method.
F1000Res
September 2025
School of Management, University of Khartoum, Khartoum, Khartoum, Sudan.
Background: At the 2020 UN General Assembly, China pledged to peak carbon emissions before 2030 and achieve carbon neutrality by 2060. However, the traditional social development model has led to increasing carbon emissions annually, highlighting the need to resolve the contradiction between development and carbon reduction. This study examines the relationship between carbon emissions, economy, population, and energy consumption in a specific region to support carbon peak and neutrality goals.
View Article and Find Full Text PDFDigital health and Buddhist network philosophy.
BJPsych Bull
September 2025
Department of Psychiatry, Kyoto University, Kyoto, Japan.
Heated online communication reveals global challenges in the digital age, often fuelled by collective outrage. This article investigates how Buddhist network perspectives, paralleling digital reality, can inform mental health. Avatamsaka philosophy provides practical ways to navigate web complexities, suggesting that individual actions ripple across society.
View Article and Find Full Text PDFRisk factors and trajectories for self-harm, neurodevelopmental disorders and mental health conditions in pupils in alternative education provision in Wales: population-based electronic cohort study.
BJPsych Open
September 2025
Swansea University Medical School, Swansea University, UK.
Background: Pupils in alternative education provision, known as 'Educated in Other Than At School' (EOTAS) in Wales, UK, are among the most vulnerable learners and who, for reasons such as mental health or behavioural challenges, do not attend a mainstream or special school.
Aims: We compared self-harm, neurodevelopmental disorders and mental health conditions between EOTAS pupils and controls with similar characteristics, before and after being in EOTAS provision.
Method: This population-based electronic cohort study included pupils in Wales aged 7-18 years, from the academic years 2010-11 to 2018-19.
Communication about sexuality for adolescents with cerebral palsy and complex communication needs: A scoping review with framework synthesis.
Dev Med Child Neurol
September 2025
School of Health and Social Development, Faculty of Health, Deakin University, Geelong, Australia.
Aim: To understand communication about sexuality for adolescents with cerebral palsy (CP) and complex communication needs.
Method: We systematically searched primary research on adolescents aged 10 to 24 years with CP and/or complex communication needs. We coded the primary evidence against themes derived from a theoretical framework analysis.