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http://dx.doi.org/10.1016/j.oraloncology.2021.105349 | DOI Listing |
Spec Care Dentist
August 2025
Department of Stomatology, School of Dentistry, University of São Paulo (USP), São Paulo, SP, Brazil.
Necrotizing sialometaplasia (NS) is a rare inflammatory condition. Despite rare, chronic self-induced vomiting in patients with eating disorders has been reported as a risk factor. This study aims to report a case of NS in a patient with bulimia nervosa and review the literature.
View Article and Find Full Text PDFLaryngoscope
July 2025
Department of Otorhinolaryngology, Head and Neck Surgery, Bürgerspital Solothurn, Solothurn, Switzerland.
PET-CT of the nasopharynx depicting not only intensive PET avidity in the right Rouvière lymph node (A: arrows) correlating with MRI findings but also increased FDG avidity at the level of the torus tubarius (B: arrows), on the right more than on the left and along the posterior nasopharyngeal wall. 3D PET image of increased metabolism along the lateral nasopharynx and torus tubarius (C: large arrow points to the right side, arrowhead to the left side; note also the avid Rouvière lymph node on the right side: short arrows). Tubarial gland location is shown in D (original scheme from Valstar, Matthijs, et al.
View Article and Find Full Text PDFSemin Diagn Pathol
September 2025
Department of Anatomic Pathology, Tokyo Medical University, Tokyo, Japan. Electronic address:
Keratosytoma is a rare, benign salivary gland tumor designated as a new entity by Nagao et al. in 2002. Recently, the discovery of RUNX2 gene rearrangement as a characteristic genetic alteration has established its classification as a distinct neoplasm, solidifying the inclusion of keratocystoma in the 5th edition of the WHO classification of Head and Neck Tumors.
View Article and Find Full Text PDFJ Clin Med
March 2025
Department of Maxillofacial Surgery and Implantology, Faculty of Dentistry, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
: Necrotizing sialometaplasia (NS) is an inflammatory condition of the salivary glands that can closely mimic malignancy. While it predominantly affects the minor salivary glands of the hard palate, it can also occur in the parotid gland, leading to potential misdiagnosis and unnecessary treatment. This study aims to analyze the characteristics, diagnostic challenges, and management of parotid gland NS through a comprehensive literature review and a case report.
View Article and Find Full Text PDFAm J Pathol
June 2025
Section of Pathology, Department of Morphological Biology, Division of Biomedical Sciences, Fukuoka Dental College, Fukuoka, Japan.
Necrotizing sialometaplasia (NSM) is a nonneoplastic lesion listed in the World Health Organization Classification of Tumours-Head and Neck Tumours. In early NSM lesion, there is infarction and necrosis of the acinar cells, and squamous metaplasia of the salivary ducts occurs as the lesion matures. Differentiation from squamous cell carcinoma and other malignancies is sometimes required clinically and histopathologically.
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