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Purpose: Attention deficit hyperactivity disorder (ADHD) is a mental health disorder commonly in children. This study aimed to examine the prevalence of ADHD and risk factors among first-year pupils in Vietnam's urban city.
Patients And Methods: A cross-sectional study was conducted in four randomly selected primary schools. Information on 525 pupils in grade 1 (ages 6 to 7 years) was collected from 525 parents/caregivers and 28 teachers. We used the Vanderbilt Assessment Scales with two separate versions for parents and teachers to screen children with ADHD symptoms.
Results: Among the total of 525 pupils, 24 (4.6%) were found to have ADHD symptom types (boy: 6.5%; girl: 2.1%). The combined ADHD type accounted for the highest proportion of 3.4%, followed by predominantly inattentive and predominantly hyperactivity type. ADHD prevalence rated by teachers was higher than those rated by parents. High agreement between parents and teachers was reported (κ > 0.6). The risk of ADHD increased in male participants (aOR=4.90, 95% CI 1.51-15.85), those having a first-degree relative with ADHD (aOR=85.2, 95% CI 1.66-4371.8), in-utero exposure to tobacco smoke (aOR=4.78, 95% CI 1.31-17.44), and prenatal alcohol drinking (aOR=8.87, 95% CI 2.29-34.42).
Conclusion: These findings suggest the importance of ADHD screening for pupils attending elementary schools, particularly those with a family history of ADHD. Public health programs should reduce prenatal exposure to the potential risk factors of ADHD (smoking and alcohol consumption).
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http://dx.doi.org/10.2147/JMDH.S301091 | DOI Listing |
Biol Psychiatry Cogn Neurosci Neuroimaging
September 2025
Developmental Imaging and Psychopathology Laboratory, University of Geneva School of medicine, Geneva, Switzerland; Department of Genetic Medicine and Development, University of Geneva School of Medicine, Geneva, Switzerland.
Background: Recent epidemiological evidence links early-life obesity and metabolic dysregulation to adult psychosis vulnerability, though a causal relationship remains unclear. Establishing causality in highly heritable psychotic disorders requires: 1) demonstrating that early-life metabolic factors mediate between genetic vulnerability and psychosis trajectory, 2) dissecting mechanisms leading to early-life obesity in genetically vulnerable individuals, and 3) clarifying downstream neurodevelopmental pathways linking early-life obesity to psychosis symptoms.
Methods: Here we investigated bidirectional pathways linking behavioral, BMI, and neurodevelopment trajectories in a unique longitudinal cohort of 184 individuals at high genetic risk for psychosis, due to 22q11.
J Affect Disord
September 2025
School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China. Electronic address:
Background: While associations between psychiatric disorders and hypothyroidism have been observed, the underlying causal relationships remain unclear. Exploring the causal relationships among them can provide new insights into the underlying mechanisms.
Methods: Two-sample Mendelian randomization (MR) was conducted to assess the causal effects of seven psychiatric disorders on hypothyroidism.
Epilepsy Res
August 2025
Department of Nursing, 2nd Medical Faculty, Charles University, Prague, Czech Republic; Department of Clinical Psychology, University Hospital Kralovske Vinohrady, Prague, Czech Republic. Electronic address:
Objective: This study investigated the prevalence of Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms in Czech adult people with epilepsy (PWE) and examined factors potentially contributing to the co-occurrence of these two conditions. Although previous research has consistently reported elevated rates of ADHD in epilepsy populations, data from adult samples in Czech Republic remain limited.
Methods: Fifty-six adults with epilepsy completed validated self-report questionnaires assessing ADHD symptoms (ASRS), anxiety (GAD-2), and depression (NDDIE-2).
J Psychiatr Res
September 2025
Genomics and Bioinformatics Group, Centre for Research in Molecular Medicine and Chronic Diseases (CiMUS), University of Santiago de Compostela (USC), Santiago de Compostela, Spain; Genetics Group, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, 15706, Spain; Fund
Methylphenidate (MPH) is the first-line treatment for Attention-Deficit/Hyperactivity Disorder (ADHD), a condition that disrupts daily functioning. Research indicates that individuals with ADHD often experience sensory processing impairments, regardless of co-occurring conditions. Given the growing interest in pharmacogenetics to personalise treatments and minimise side effects, this study aims to characterise the sensory profiles of in child and youth ADHD patients treated with MPH and investigate potential pharmacogenetic biomarkers that could be associated with treatment outcomes or sensory-related side effects.
View Article and Find Full Text PDFSleep Med
September 2025
Regional Epilepsy Center, Operative Unit of Childhood and Adolescent Neuropsychiatry, ASST Spedali Civili di Brescia, Brescia, Italy.
Background: Sleep disturbances are highly prevalent in children with neurodevelopmental disorders (NDD), yet few studies have combined objective and subjective measures. The objectives of this study were to evaluate sleep patterns and sleep hygiene in children with ADHD and ASD compared age-matched typically developing children, using both parent-reported questionnaires and actigraphy, to assess the concordance between these measures, and to determine the clinical applicability of actigraphy in this population.
Methods: Sixty children with NDD (30 ASD, 30 ADHD) and 40 typically developing controls, matched for age, underwent seven nights of actigraphic recording.