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One of the problems during surgery for intramedullary lipoma is the ambiguous boundary between the lipoma and the spinal cord, resulting in either incomplete resection or damage to the spinal cord. We report a case of intramedullary lipoma resection on a 61-year-old man in which the boundary between the tumor and spinal cord was repeatedly visualized with intraoperative ultrasonography. We focused on the distinctive features of fat as hyperechoic, in contrast to low-echo neural tissue. Subtotal resection of the tumor was achieved without any aggravation of neurological symptoms. Intraoperative ultrasonography may be useful for confirming tumor boundaries during intramedullary lipoma resection.
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http://dx.doi.org/10.18926/AMO/61907 | DOI Listing |
J Neurosurg Spine
September 2025
Departments of1Neurological Surgery and.
Objective: The rate of dorsal column deficit after intramedullary spine tumor resection remains unknown. In a cohort of patients undergoing posterior intramedullary spinal tumor resection, the authors sought to 1) report the rate of dorsal column deficits, 2) report the rate of new motor deficits, and 3) determine risk factors and recovery characteristics for both deficits.
Methods: A single-institution, retrospective cohort study of patients undergoing posterior intramedullary spinal cord tumor resection was performed from 2010 to 2020.
Medicina (B Aires)
January 2025
Hospital General de Agudos José M. Ramos Mejía, Buenos Aires, Argentina.
J Extracell Vesicles
June 2025
GMP Unit, Paracelsus Medical University, Salzburg, Austria.
Spina bifida is a congenital neural tube defect that has a high risk of secondary neurological deterioration due to tethering of the spinal cord. We present the first application of human umbilical cord-derived mesenchymal stromal cell-derived extracellular vesicle (UC-MSC-EV) therapy in humans during spina bifida surgery. We discuss the application, post-operative outcome and highlight the potential of extracellular vesicle therapy in the management of spina bifida.
View Article and Find Full Text PDFWorld Neurosurg
October 2024
Department of Surgery, St. Jude Children's Research Hospital, Memphis, Tennessee, USA; Le Bonheur Neuroscience Institute, Le Bonheur Children's Hospital, Memphis, Tennessee, USA; Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA; Semmes-Murphey Clinic
Objective: Intramedullary spinal cord lipomas without spinal dysraphism are rare. Although they are benign tumors, they can cause significant neurological deficits. Their tight adherence to the spinal cord presents a challenge for resection.
View Article and Find Full Text PDFAnn Med Surg (Lond)
June 2024
Department of Neurosurgery, Tribhuvan University Institute of Medicine, Maharajgunj, Nepal.
Introduction: Intramedullary nondysraphic spinal lipomas are extremely rare among primary spinal cord tumors. These patients present with nonspecific sensory symptoms followed by deterioration of motor symptoms. As the safety margins for neurological preservation are thin, meticulously locating the extent of the tumor and choosing the resection modalities is essential.
View Article and Find Full Text PDF