Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1136/rapm-2021-102692DOI Listing

Publication Analysis

Top Keywords

characterizing multiple
4
multiple epidural
4
epidural blood
4
blood patches
4
patches treatment
4
treatment postdural
4
postdural puncture
4
puncture headache
4
headache observational
4
observational study
4

Similar Publications

Background: Between November 2023 and March 2024, coastal Kenya experienced another wave of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections detected through our continued genomic surveillance. Herein, we report the clinical and genomic epidemiology of SARS-CoV-2 infections from 179 individuals (a total of 185 positive samples) residing in the Kilifi Health and Demographic Surveillance System (KHDSS) area (~ 900 km).

Methods: We analyzed genetic, clinical, and epidemiological data from SARS-CoV-2 positive cases across pediatric inpatient, health facility outpatient, and homestead community surveillance platforms.

View Article and Find Full Text PDF

Cell death in multiple sclerosis.

Cell Death Differ

September 2025

Department of Neurology, Tianjin Neurological Institute, Tianjin Medical University General Hospital, Tianjin, China.

Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system (CNS) characterized by inflammatory demyelination and progressive neurodegeneration. Although current disease-modifying therapies modulate peripheral autoimmune responses, they are insufficient to fully prevent tissue specific neuroinflammation and long-term neuronal and oligodendrocyte loss. Growing evidence implicates various regulated cell death (RCD) pathways, including apoptosis, necroptosis, pyroptosis, and ferroptosis, not only as downstream consequences of chronic inflammation, but also as active drivers of demyelination, axonal injury, and glial dysfunction in MS.

View Article and Find Full Text PDF

Communities of plasmids as strategies for antimicrobial resistance gene survival in wastewater treatment plant effluent.

NPJ Antimicrob Resist

September 2025

Antimicrobial Resistance & Microbiome Research Group, Department of Biology, The Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co, Kildare, Ireland.

Plasmids facilitate antimicrobial resistance (AMR) gene spread via horizontal gene transfer, yet the mobility of genes in wastewater treatment plant (WWTP) resistomes remains unclear. We sequenced 173 circularised plasmids transferred from WWTP effluent into Escherichia coli and characterised their genetic content. Multiple multidrug-resistant plasmids were identified, with a significant number of mega-plasmids (>100 kb).

View Article and Find Full Text PDF

Petit-spot volcanism plays a critical role in the metasomatism of oceanic plates prior to subduction and in their recycling into the deep mantle. The extent of metasomatism depends on the number and volume of petit-spot volcanic edifices and intrusions, making precise identification of petit-spot volcanic fields essential. However, conventional methods based on seafloor topography and acoustic backscatter intensity alone have limitations in accurately delineating these features.

View Article and Find Full Text PDF

Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS). The latter is a human organ-specific autoimmune disease of the central nervous system (CNS). EAE is characterized by systemic inflammation associated with increased blood levels of proinflammatory mediators that potentially trigger inflammation of both reproductive organs and the CNS.

View Article and Find Full Text PDF