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Background: In response to the rising global NCD burden, humanitarian actors have rapidly scaled-up NCD services in crisis-affected low-and-middle income countries. Using the RE-AIM implementation framework, we evaluated a multidisciplinary, primary level model of NCD care for Syrian refugees and vulnerable Jordanians delivered by MSF in Irbid, Jordan. We examined the programme's Reach, Effectiveness, Adoption and acceptance, Implementation and Maintenance over time.
Methods: This mixed methods retrospective evaluation, undertaken in 2017, comprised secondary analysis of pre-existing cross-sectional household survey data; analysis of routine cohort data from 2014 to 2017; descriptive costing analysis of total annual, per-patient and per-consultation costs for 2015-2017 from the provider-perspective; a clinical audit; a medication adherence survey; and qualitative research involving thematic analysis of individual interviews and focus group discussions.
Results: The programme enrolled 23% of Syrian adult refugees with NCDs in Irbid governorate. The cohort mean age was 54.7 years; 71% had multi-morbidity and 9.9% self-reported a disability. The programme was acceptable to patients, staff and stakeholders. Blood pressure and glycaemic control improved as the programme matured and by 6.6 mmHg and 1.12 mmol/l respectively within 6 months of patient enrolment. Per patient per year cost increased 23% from INT$ 1424 (2015) to 1751 (2016), and by 9% to 1904 (2017). Cost per consultation increased from INT$ 209 to 253 (2015-2017). Staff reported that clinical guidelines were usable and patients' self-reported medication adherence was high. Individual, programmatic and organisational challenges to programme implementation and maintenance included the impact of war and the refugee experience on Syrian refugees' ability to engage; inadequate low-cost referral options; and challenges for MSF to rapidly adapt to operating in a highly regulated and complex health system. Essential programme adaptations included refinement of health education, development of mental health and psychosocial services and addition of essential referral pathways, home visit, physiotherapy and social worker services.
Conclusion: RE-AIM proved a valuable tool in evaluating a complex intervention in a protracted humanitarian crisis setting. This multidisciplinary programme was largely acceptable, achieving good clinical outcomes, but for a limited number of patients and at relatively high cost. We propose that model simplification, adapted procurement practices and use of technology could improve cost effectiveness without reducing acceptability, and may facilitate replication.
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http://dx.doi.org/10.1186/s12913-021-06333-3 | DOI Listing |
Prev Med
September 2025
Department of Pharmacy, Taoyuan General Hospital, Ministry of Health and Welfare, No. 1492, Zhongshan Rd., Taoyuan 33004, Taiwan. Electronic address:
Objective: Middle-aged and older adults living with HIV in the Western Pacific Region (WPR) are experiencing accelerated aging and a rising burden of non-communicable disease (NCD)-related comorbidities. This systematic review and meta-analysis aimed to assess the burden of major NCDs-measured by prevalence, incidence, and mortality-among people living with HIV(PLWH) aged 40 years and older, in comparison to their HIV-negative counterparts.
Methods: A comprehensive literature search was conducted across Medline (1966-), Embase (1974-), Cochrane Library (1996-), Epistemonikos (established in 2012, with retrospective coverage), and Web of Science (1900-) to identify relevant studies published up to May 9, 2025.
BMC Health Serv Res
September 2025
Kamuzu University of Health Sciences, Blantyre, Malawi.
Background: Non-communicable diseases (NCDs) in children are becoming the leading cause of morbidity and mortality globally. Low- and middle-income countries have not been spared. To improve the quality of care, there is need to use evidence-based and locally relevant interventions.
View Article and Find Full Text PDFHypertens Res
September 2025
Department of Preventive Medicine and Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
We previously conducted a systematic review and meta-analysis examining the effects of smartphone application-based interventions on blood pressure (BP). Building on that work, here we present a secondary analysis which explored the effects of these interventions on cardiometabolic risk factors. We searched MEDLINE, the Cochrane Library, and Ichushi for randomized controlled trials and observational studies comparing smartphone application-based interventions with usual care excluding digital technologies.
View Article and Find Full Text PDFPLoS One
September 2025
Division of NCD, Indian Council of Medical Research, New Delhi, India.
Introduction: Integrated emergency care systems are essential for achieving universal health coverage and managing time-sensitive conditions. In India, emergency care remains fragmented, with limited resources and coordination across healthcare tiers. The INDIA-EMS study aims to develop and evaluate a patient-centric, high-quality integrated emergency care model in diverse Indian districts.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
September 2025
Division of Epidemiology and Biostatistics, School of Public Health, University of Cape Town, Falmouth Building, Anzio Road, Observatory , Cape Town , Western Cape , 7925, South Africa.
Background: Despite improved health and survival due to lifelong antiretroviral therapy (ART), women living with HIV (WHIV) still face lower life expectancy, partly due to increased non-communicable disease (NCD) risk. Both HIV and NCDs are linked to adverse birth outcomes, yet data on their combined impact are limited. We investigated NCD burden by HIV status and compared adverse birth outcomes in pregnant WHIV only versus HIV-NCD comorbidity in Cape Town, South Africa.
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