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One sub-population potentially affected by the COVID-19 pandemic are strength athletes who use anabolic-androgenic steroids (AAS). We examined links between disruption in AAS use and training due to the pandemic and mental health outcomes in this population, hypothesising: (a) the pandemic would be linked with reduced training and AAS use; and (b) athletes perceiving greater impact on their training and AAS use would report increases in detrimental mental health outcomes. Male strength athletes using AAS ( = 237) from 42 countries completed an online questionnaire in May 2020. A sub-sample ( = 90) from 20 countries participated again 4 months later. The questionnaire assessed pre-pandemic and current AAS use and training, alongside several mental health outcomes. At Time 1, most participants perceived an impact of the pandemic on AAS use (91.1%) and/or training (57.8%). Dependent -tests demonstrated significant reductions in training frequency ( = 7.78; < 0.001) and AAS dose ( = 6.44; < 0.001) compared to pre-pandemic. Linear regression showed the impact of the pandemic on training was a significant positive predictor of excessive body checking ( = 0.35) and mood swings ( = 0.26), and AAS dose was a significant positive predictor of anxiety ( = 0.67), insomnia ( = 0.52), mood swings ( = 0.37). At Time 2, fewer participants perceived an impact of the pandemic on AAS use (29.9%) and/or training (66.7%) than at Time 1. Training frequency ( = 3.02; < 0.01) and AAS dose ( = 2.11; < 0.05) were depressed in comparison to pre-pandemic. However, AAS dose had increased compared to Time 1 ( = 2.11; < 0.05). Linear regression showed the impact of the pandemic on training/AAS use did not significantly predict any mental-health outcomes. However, AAS dose was a significant negative predictor of depressive thoughts ( = -0.83) and mood swings ( = -2.65). Our findings showed impact of the pandemic on the training and AAS use, reflected in reduced training frequency and AAS dose. However, whilst we detected some short-term consequential effects on mental health, these did not appear to be long-lasting.
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http://dx.doi.org/10.3389/fpsyt.2021.636706 | DOI Listing |
Vasa
September 2025
Rhein Main Vascular Center, Department of Vascular and Endovascular Surgery, Asklepios Clinics Langen, Paulinen Wiesbaden, Seligenstadt, Germany.
Endovascular aortic aneurysm repair (EVAR) has evolved into a widely established alternative to traditional open surgical repair. For EVAR procedures, both mobile (standard operating room (SOR)) and fixed C-arm (hybrid operating room (HOR) systems are available. The aim of our study was to evaluate the advantages of implementing a HOR for endovascular aortic aneurysm repair at a new vascular surgery centre.
View Article and Find Full Text PDFNutrients
August 2025
Birmingham Children's Hospital, NHS Trust, Steelhouse Lane, Birmingham B4 6NH, UK.
: The rate at which amino acids (AAs) are absorbed from casein glycomacropeptide (CGMP) when given as a protein substitute in phenylketonuria (PKU) is unknown. This three-way randomised, controlled, crossover study aimed to compare the AA absorption profile of phenylalanine (Phe)-free L-amino acids (L-AAs), low-Phe CGMP (CGMP) and casein in healthy adult subjects. : Area under the curve (AUC) was measured over 240 minutes after ingesting one dose of each protein source on three separate occasions, under the same test conditions.
View Article and Find Full Text PDFCells
August 2025
Biomedical Research Center, QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
N-lactoyl amino acids (Lac-AAs) are key players that regulate appetite and body weight. The most prominent and well-studied member is N-lactoyl phenylalanine (Lac-Phe), which can be induced by food intake, exercise and metformin treatment. However, its broader metabolic impact remains insufficiently characterized.
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November 2025
Jiangsu Marine Pharmaceutical Resources Development Engineering Research Center, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China. Electronic address:
Chronic intermittent hypoxia (CIH) caused by obstructive sleep apnea (OSA) exacerbates renal dysfunction, fibrosis, and chronic kidney disease (CKD) progression. This study investigates the renoprotective effects and mechanisms of atraric acid (AA), a natural compound from oakmoss with anti-inflammatory and antioxidant properties, against CIH-induced renal injury. A CIH mouse model was established, with groups including control, CIH, and CIH mice treated with AA (5, 10, 20 mg/kg).
View Article and Find Full Text PDFCurr Res Parasitol Vector Borne Dis
June 2025
Department of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Elizabeth Stephansens vei 15, Aas, 1433, Norway.
is a major pathogen responsible for neonatal calf diarrhoea, but research has been hampered due to the lack of models that can complete the life cycle. In this scenario, human and murine small intestinal organoids (enteroids) are emerging as new tools. However, models employing bovine cells, relevant for the pathogenesis in the target species, are lacking.
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