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Article Abstract
Translocation between sex-chromosomes and autosomes generates multiple sex-chromosome systems. It happens unexpectedly, and therefore, the evolutionary meaning is not clear. The current study shows a multiple sex chromosome system comprising three different chromosome pairs in a Taiwanese brown frog (). The male-specific three translocations created a system of six sex-chromosomes, ♂XYXYXY-♀XXXXXX. It is unique in that the translocations occurred among three out of the six members of potential sex-determining chromosomes, which are known to be involved in sex-chromosome turnover in frogs, and the two out of three include orthologs of the sex-determining genes in mammals, birds and fishes. This rare case suggests sex-specific, nonrandom translocations and thus provides a new viewpoint for the evolutionary meaning of the multiple sex chromosome system.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002213 | PMC |
| http://dx.doi.org/10.3390/cells10030661 | DOI Listing |
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